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Fmoc-3-nitro-L-tyrosine (CAS 136590-09-5)

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Alternate Names:
Fmoc-Tyr(3-NO2)-OH
CAS Number:
136590-09-5
Molecular Weight:
448.42
Molecular Formula:
C24H20N2O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fmoc-3-nitro-L-tyrosine (Fmoc-3NT) is a synthetic amino acid widely employed in various scientific applications. Derived from tyrosine, an essential amino acid, Fmoc-3-nitro-L-tyrosine stands out due to its versatile modifiability. It finds extensive utility in laboratory experiments encompassing protein synthesis, peptide synthesis, and enzyme assays. In scientific research, Fmoc-3-nitro-L-tyrosine finds utility across diverse applications. It serves as useful for investigating protein structure and function, facilitating protein and peptide modifications. Additionally, Fmoc-3-nitro-L-tyrosine is employed in enzyme assays, enabling enzyme modification to enhance activity or explore structure-function relationships. Fmoc-3-nitro-L-tyrosine, a small molecule possessing an amino group, a nitro group, and a carboxyl group, can modify proteins and peptides. When introduced to a peptide or protein, the amino group reacts with the carboxyl group, forming a covalent bond. This covalent bond imparts structural and functional modifications to the peptide or protein, enhancing its activity or altering its properties.


Fmoc-3-nitro-L-tyrosine (CAS 136590-09-5) References

  1. Anthranilamide and nitrotyrosine as a donor-acceptor pair in internally quenched fluorescent substrates for endopeptidases: multicolumn peptide synthesis of enzyme substrates for subtilisin Carlsberg and pepsin.  |  Meldal, M. and Breddam, K. 1991. Anal Biochem. 195: 141-7. PMID: 1888010
  2. Comparative studies of adhesion peptides based on l- or d-amino acids.  |  Nikitin, S., et al. 2016. J Pept Sci. 22: 642-646. PMID: 27580849

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fmoc-3-nitro-L-tyrosine, 1 g

sc-472088
1 g
$23.00

Fmoc-3-nitro-L-tyrosine, 5 g

sc-472088A
5 g
$71.00

Fmoc-3-nitro-L-tyrosine, 25 g

sc-472088B
25 g
$173.00

Fmoc-3-nitro-L-tyrosine, 100 g

sc-472088C
100 g
$1163.00