Fluvoxamine (CAS 54739-18-3)
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Fluvoxamine is a compound with a significant role in chemical and neurological research, known for its strong affinity for the serotonin transporter (SERT). It is utilized in studies that examine the modulation of serotonin levels and the regulation of serotonin reuptake mechanisms. This research is for understanding the intricate balance of neurotransmitters and the impact on synaptic transmission. Additionally, fluvoxamine is employed as a tool in neurochemical studies to understand the molecular underpinnings of mood regulation and the function of serotonergic systems. It is also of interest in the field of neuropharmacology, where it provides a model for studying the binding profiles of potential compounds that interact with the serotonin transporter. Furthermore, fluvoxamine is utilized in the synthesis of analogs to probe the structure-activity relationship of SERT ligands, contributing to the fundamental knowledge of how structural changes can affect transporter binding and activity.
Fluvoxamine (CAS 54739-18-3) References
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- Fluvoxamine maleate normalizes striatal neuronal inflammatory cytokine activity in a Parkinsonian rat model associated with depression. | Dallé, E., et al. 2017. Behav Brain Res. 316: 189-196. PMID: 27569183
- Fluvoxamine, a specific 5-hydroxytryptamine uptake inhibitor. | Claassen, V., et al. 1977. Br J Pharmacol. 60: 505-16. PMID: 302726
- Fluvoxamine is a potent inhibitor of cytochrome P4501A2. | Brøsen, K., et al. 1993. Biochem Pharmacol. 45: 1211-4. PMID: 8466541
- Reduction of serotonergic function in rat brain by tryptophan depletion: effects in control and fluvoxamine-treated rats. | Bel, N. and Artigas, F. 1996. J Neurochem. 67: 669-76. PMID: 8764594
- Pharmacokinetic interactions of clozapine with selective serotonin reuptake inhibitors: differential effects of fluvoxamine and paroxetine in a prospective study. | Wetzel, H., et al. 1998. J Clin Psychopharmacol. 18: 2-9. PMID: 9472836
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fluvoxamine, 25 mg | sc-207697 | 25 mg | $315.00 |