Molecular structure of Fluticasone 17β-Carboxylic Acid Propionate, CAS Number: 65429-42-7
Fluticasone 17β-Carboxylic Acid Propionate (CAS 65429-42-7)
Alternate Names:
(6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-androsta-1,4-diene-17-carboxylic Acid
Application:
Fluticasone 17β-Carboxylic Acid Propionate is An impurity formed in the synthesis of Fluticasone propionate
CAS Number:
65429-42-7
Molecular Weight:
452.49
Molecular Formula:
C24H30F2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Fluticasone 17β-Carboxylic Acid Propionate is an impurity formed in the synthesis of Fluticasone propionate. Studies focused on this impurity contribute to optimizing synthesis protocols to minimize its production. Analytical techniques such as high-performance liquid chromatography (HPLC), mass spectrometry (MS), and nuclear magnetic resonance (NMR) spectroscopy play pivotal roles in detecting and quantifying this impurity.
Fluticasone 17β-Carboxylic Acid Propionate (CAS 65429-42-7) References
- Liquid chromatography-tandem mass spectrometry analysis of urinary fluticasone propionate-17beta-carboxylic acid for monitoring compliance with inhaled-fluticasone propionate therapy. | Korpi-Steiner, NL., et al. 2010. Steroids. 75: 77-82. PMID: 19883673
- Urinary fluticasone propionate-17beta-carboxylic acid to assess asthma therapy adherence. | Hagan, JB., et al. 2012. Allergy Asthma Proc. 33: e35-9. PMID: 22856629
- Adrenal insufficiency in a woman secondary to standard-dose inhaled fluticasone propionate therapy. | Hay, CM. and Spratt, DI. 2014. Endocrinol Diabetes Metab Case Rep. 2014: 130080. PMID: 24683484
- Simultaneous analysis of glucocorticosteroid fluticasone propionate and its metabolite fluticasone propionate 17β-carboxylic acid in human plasma by UPLC-MS/MS at sub pg/mL level. | Nair, SG., et al. 2017. J Pharm Biomed Anal. 135: 1-7. PMID: 27987390
- HPLC-UV and spectrofluorimetric methods for simultaneous estimation of fluticasone furoate and vilanterol in rabbit plasma: A pharmacokinetic study. | Patel, D., et al. 2019. J Chromatogr B Analyt Technol Biomed Life Sci. 1132: 121842. PMID: 31669821
- Effects of Fluticasone Propionate on Klebsiella pneumoniae and Gram-Negative Bacteria Associated with Chronic Airway Disease. | Begley, LA., et al. 2022. mSphere. 7: e0037722. PMID: 36342141
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fluticasone 17β-Carboxylic Acid Propionate, 100 mg | sc-489894 | 100 mg | $400.00 |