Flutax 1 CAS: 191930-58-2
MF: C71H66N2O21
MW: 1283.28
A fluorescent taxol derivative.

Flutax 1 (CAS 191930-58-2)

Flutax 1 | CAS 191930-58-2 is rated 5.0 out of 5 by 1.
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Alternate Names: 7-O-[N-(4Fluoresceincarbonyl)-L-alanyl]Taxol
Application: Flutax 1 is a fluorescent taxol derivative
CAS Number: 191930-58-2
Purity: ≥98%
Molecular Weight: 1283.28
Molecular Formula: C71H66N2O21
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Flutax 1 is a fluorescent taxol (sc-201439) derivative that binds to the taxol microtubule binding site with high affinity (Ka ~ 107M-1). This chemical is useful for direct imaging of the microtubule cytoskeleton.


References

1. Evangelio, J.A., et al. 1998. Cell Motil. Cytoskeleton. 39: 73-90. PMID: 9453715
2. Díaz, J.F., et al. 2000. J. Biol. Chem. 275: 26265-26276. PMID: 10818101
3. Díaz, J.F., et al. 2003. J. Biol. Chem. 278: 8407-8419. PMID: 12496245

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), and ethanol (100 mM).
Storage :
Store at -20° C
Refractive Index :
n20D 1.69 (Predicted)
Fluoresence :
λex 495 nm, λem 520 nm
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
16760423
SMILES :
CC1=C2[[email protected]](C(=O)[[email protected]@]3([[email protected]@H](C[[email protected]@H]4[[email protected]]([[email protected]]3[[email protected]@H]([[email protected]@](C2(C)C)(C[[email protected]@H]1OC(=O)[[email protected]@H]([[email protected]](C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)OC(=O)[[email protected]](C)NC(=O)C8=CC(=C(C=C8)C9=C1C=CC(=O)C=C1OC1=C9C=CC(=C1)O)C(=O)O)C)OC(=O)C

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Certificate of Analysis

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Flutax 1 (CAS 191930-58-2)  Product Citations

See how others have used Flutax 1 (CAS 191930-58-2). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 25222296  Brodie, SA. et al. 2014. PloS one. 9: e107124.

PMID: # 31847101  Cancers (Basel). 11:

Citations 1 to 2 of 2 total
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Rated 5 out of 5 by from Diaz et al Diaz et al. (PubMed ID 10818101) showed that Flutax 1 bound to microtubuiles and elucidated taxol binding site accessibility and reaction rates. -SCBT Publication Review
Date published: 2015-02-19
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