Fluphenazine-d8 Dihydrochloride

Fluphenazine-d8 Dihydrochloride is a deuterium-labeled form of Fluphenazine dihydrochloride. Fluphenazine dihydrochloride belongs to the phenothiazine class and acts as an inhibitor of D1DR and D2DR receptors. It is employed in research to investigate the impact and metabolic pathways of this well-known dopamine antagonist. The incorporation of deuterium atoms into compounds like fluphenazine can enhance the analytical detection and measurement of these compounds within biological matrices, making Fluphenazine-d8 Dihydrochloride particularly valuable in kinetic and dynamic studies. In such research, it serves as an internal standard that allows for more accurate and precise quantification of fluphenazine levels when analyzed through techniques such as mass spectrometry (MS) or high-performance liquid chromatography (HPLC). The deuterated compound behaves similarly to the non-deuterated version in biological systems but can be distinctly identified and measured due to the mass difference imparted by deuterium.