Date published: 2026-3-6

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Fluoxetine-d5 Hydrochloride (CAS 1173020-43-3)

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Application:
Fluoxetine-d5 Hydrochloride is a deuterium-labeled analog of Fluoxetine
CAS Number:
1173020-43-3
Molecular Weight:
350.82
Molecular Formula:
C17H14D5ClF3NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(S)-Fluoxetine Hydrochloride is a deuterium-labeled isomer of Fluoxetine (sc-201125). Fluoxetine is a 5-hydroxytryptamine (serotonin, 5-HT) reuptake inhibitor. This compound is a racemic mixture and both R and S enantiomers are reported to inhibit 5-HT uptake in synaptosomal preparations of rat cerebral cortex. Fluoxetine is also noted to be a highly selective, sodium dependent, 5-HT transporter in studies of rat cerebrums. Additionally, Fluoxetine is also noted to increase extracellular levels of 5-HT in several areas of the rat brain as a result of reuptake inhibition. This increase in availability of 5-HT is reported to lead to a decrease in synthesis and turnover of 5-HT. Also available as unlabeled (R)-Fluoxetine Hydrochloride (sc-208240) and (S)-Fluoxetine Hydrochloride (sc-208367)


Fluoxetine-d5 Hydrochloride (CAS 1173020-43-3) References

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  6. Development of a method for assessing the accumulation and metabolization of antidepressant drugs in zebrafish (Danio rerio) eleutheroembryos.  |  Molina-Fernández, N., et al. 2021. Anal Bioanal Chem. 413: 5169-5179. PMID: 34195876
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  8. The metabolites could not be ignored: A comparative study of the metabolite norfluoxetine with its parent fluoxetine on zebrafish (Danio rerio).  |  Yan, Z., et al. 2023. Aquat Toxicol. 257: 106467. PMID: 36870174
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fluoxetine-d5 Hydrochloride, 1 mg

sc-218509
1 mg
$330.00