Fluoro 2-Deoxy-2-fluoro-3,4,6-tri-O-acetyl-D-glucose (CAS 86786-39-2)

Fluoro 2-Deoxy-2-fluoro-3,4,6-tri-O-acetyl-D-glucose is a valuable compound extensively employed in organic synthesis and medicinal chemistry research. Its chemical structure, featuring a fluorinated sugar moiety, lends unique properties that make it useful in various scientific investigations. One of its primary applications lies in positron emission tomography (PET) imaging, where it serves as a precursor for the synthesis of radiolabeled tracers for visualizing glucose metabolism in living organisms. By incorporating a positron-emitting radionuclide into its structure, such as fluorine-18 (^18F), this compound enables the production of ^18F-labeled glucose analogs that can be administered intravenously to monitor glucose uptake and utilization in tissues using PET imaging. This capability is crucial for studying metabolic processes in healthy and diseased states, including cancer, cardiovascular diseases, and neurological disorders. Furthermore, Fluoro 2-Deoxy-2-fluoro-3,4,6-tri-O-acetyl-D-glucose serves as a versatile building block in the synthesis of fluorinated carbohydrate derivatives and glycoconjugates for investigating structure-activity relationships, developing new diagnostic tools, and exploring carbohydrate-mediated biological interactions. Its role in PET imaging and carbohydrate chemistry highlights its significance in advancing research across diverse fields, from molecular biology to medical imaging.