Date published: 2026-4-28

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Flunixin (CAS 38677-85-9)

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Alternate Names:
2-[2-Methyl-3-(trifluoromethyl)phenylamino]nicotinic acid
CAS Number:
38677-85-9
Molecular Weight:
296.24
Molecular Formula:
C14H11F3N2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Flunixin is a compound of note within veterinary research, primarily focusing on its anti-inflammatory and analgesic properties. It is studied for its mechanism of action, which involves the inhibition of the cyclooxygenase enzyme, leading to a decrease in the production of prostaglandins that mediate inflammation and pain. Research involving Flunixin includes its chemical kinetics and dynamics, providing critical information on its metabolism and excretion. In addition, Flunixin is used in research to understand the impact of nonsteroidal anti-inflammatory drugs (NSAIDs) on animal physiology, including their effects on the gastrointestinal tract and kidneys.


Flunixin (CAS 38677-85-9) References

  1. Palatability and pharmacokinetics of flunixin when administered to sheep through feed.  |  Marini, D., et al. 2016. PeerJ. 4: e1800. PMID: 26989633
  2. The pharmacokinetics of transdermal flunixin meglumine in Holstein calves.  |  Kleinhenz, MD., et al. 2016. J Vet Pharmacol Ther. 39: 612-615. PMID: 27121728
  3. Effects of flunixin meglumine on postponement of ovulation in mares.  |  Donnelly, CG., et al. 2019. Am J Vet Res. 80: 306-310. PMID: 30801209
  4. Death of captive-bred vultures caused by flunixin poisoning in Italy.  |  Eleni, C., et al. 2019. Environ Toxicol Pharmacol. 68: 91-93. PMID: 30878718
  5. Pharmacokinetics of transdermal flunixin in sows.  |  Cramer, MC., et al. 2019. J Vet Pharmacol Ther. 42: 492-495. PMID: 31197844
  6. Effect of rain on absorption after transdermal application of flunixin in calves.  |  Altenbrunner-Martinek, B., et al. 2020. J Vet Pharmacol Ther. 43: 87-90. PMID: 31833566
  7. Plasma, urine and tissue concentrations of Flunixin and Meloxicam in Pigs.  |  Nixon, E., et al. 2020. BMC Vet Res. 16: 340. PMID: 32938437
  8. PHARMACOKINETICS OF ORALLY ADMINISTERED FLUNIXIN MEGLUMINE IN AFRICAN (LOXODONTA AFRICANA) AND ASIAN (ELEPHAS MAXIMUS) ELEPHANTS.  |  Bechert, U., et al. 2021. J Zoo Wildl Med. 51: 905-914. PMID: 33480571
  9. Pharmacokinetics of transdermal flunixin meglumine and effects on biomarkers of inflammation in horses.  |  Knych, HK., et al. 2021. J Vet Pharmacol Ther. 44: 745-753. PMID: 34173263
  10. Medication control of flunixin in racing horses: Possible detection times using Monte Carlo simulations.  |  Kuroda, T., et al. 2022. Equine Vet J. 54: 979-988. PMID: 34719043
  11. Pharmacokinetic/pharmacodynamic modeling of ketoprofen and flunixin at piglet castration and tail-docking.  |  Nixon, E., et al. 2022. J Vet Pharmacol Ther. 45: 450-466. PMID: 35833463
  12. Efficacy of transdermal flunixin in mitigating castration pain in piglets.  |  Lopez-Soriano, M., et al. 2022. Front Pain Res (Lausanne). 3: 1056492. PMID: 36438445
  13. Flunixin in the cat: a pharmacodynamic, pharmacokinetic and toxicological study.  |  Taylor, PM., et al. 1994. Br Vet J. 150: 253-62. PMID: 8044665

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Flunixin, 100 mg

sc-235149
100 mg
$215.00