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Flumethasone pivalate (CAS 2002-29-1)

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Alternate Names:
6α,9-Difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(2,2-dimethylpropionate)
Application:
Flumethasone pivalate is a GR (glucocorticoid receptor) agonist
CAS Number:
2002-29-1
Molecular Weight:
494.57
Molecular Formula:
C27H36F2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Flumethasone pivalate is a compound that is primarily investigated in the field of biochemistry for its interaction with various cellular pathways. It is studied for its binding affinity to protein receptors and the resultant effects on gene expression within cells. Researchers are interested in the compound′s potential to modulate inflammatory responses as well as its influence on cellular proliferation and differentiation. In addition, Flumethasone pivalate is used in studies aiming to understand the mechanisms of signal transduction related to its activity. Its structural and functional properties are also analyzed to determine how they contribute to its interactions with biological membranes and proteins.


Flumethasone pivalate (CAS 2002-29-1) References

  1. Differences in prescribing between GPs: impact of the cooperation with pharmacists and impact of visits from pharmaceutical industry representatives.  |  Muijrers, PE., et al. 2005. Fam Pract. 22: 624-30. PMID: 16055474
  2. Multinuclear NMR characterisation and dermal delivery of fluorinated drugs in soybean-microemulsion systems.  |  Hoeller, S., et al. 2009. J Pharm Sci. 98: 2686-95. PMID: 19105222
  3. Novel spectrophotometric determination of flumethasone pivalate and clioquinol in their binary mixture and pharmaceutical formulation.  |  Abdel-Aleem, EA., et al. 2015. Spectrochim Acta A Mol Biomol Spectrosc. 136 Pt B: 707-13. PMID: 25448970
  4. Occurrence of Glucocorticoids, Mineralocorticoids, and Progestogens in Various Treated Wastewater, Rivers, and Streams.  |  Weizel, A., et al. 2018. Environ Sci Technol. 52: 5296-5307. PMID: 29580053
  5. Interventions for infantile seborrhoeic dermatitis (including cradle cap).  |  Victoire, A., et al. 2019. Cochrane Database Syst Rev. 3: CD011380. PMID: 30828791
  6. Comparative study of novel green UV-spectrophotometric platforms for simultaneous rapid analysis of flumethasone pivalate and clioquinol in their combined formulation.  |  A Sayed, R., et al. 2021. Drug Dev Ind Pharm. 47: 867-877. PMID: 34224277
  7. [Experimental study on transcutaneous reabsorption and the possible effect of flumethasone pivalate on the hypophysis-adrenal gland axis].  |  Ormea, F., et al. 1967. Minerva Dermatol. 42: 625-6. PMID: 5309594
  8. Effects of various synthetic glucocorticoids on milk production and blood glucose and ketone body concentrations in normal and ketotic cows.  |  Braun, RK., et al. 1970. J Am Vet Med Assoc. 157: 941-6. PMID: 5528652
  9. Betamethasone dipropionate with salicylic acid and flumethasone pivalate with salicylic acid in steroid responsive dermatoses demanding keratolytic penetration.  |  Mattila, R. 1980. J Int Med Res. 8: 247-50. PMID: 6993254
  10. [Effect of salicylic acid on the blanching effect of flumethasone pivalate (author's transl)].  |  Wienert, V. and Blazek, V. 1981. Arch Dermatol Res. 271: 19-27. PMID: 7294880

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Flumethasone pivalate, 100 mg

sc-235147
100 mg
$183.00