Date published: 2026-1-11

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Fludrocortisone (CAS 127-31-1)

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Application:
Fludrocortisone is A mineralocorticoid
CAS Number:
127-31-1
Molecular Weight:
380.45
Molecular Formula:
C21H29FO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fludrocortisone is a mineralocorticoid. In the realm of analytical chemistry, fludrocortisone can be used as a reference or standard compound in chromatographic analyses to help identify and quantify the presence of similar compounds in mixtures. Additionally, due to its stability and structural features, fludrocortisone could be employed in studies focusing on the behavior of synthetic compounds under different environmental conditions. This includes examining its degradation products or its interactions with other chemical agents, which can provide valuable data for environmental chemistry studies. In materials science, fludrocortisone might be explored for its potential in the synthesis of novel organic materials, possibly serving as a precursor or an additive that modifies properties like tensile strength or chemical resistance in polymers.


Fludrocortisone (CAS 127-31-1) References

  1. Stability of fludrocortisone acetate solutions prepared from tablets and powder.  |  Cisternino, S., et al. 2003. Eur J Pharm Biopharm. 55: 209-13. PMID: 12637099
  2. Effect of stress on response to fludrocortisone excess in the rat.  |  HALL, CE. and HALL, O. 1961. Proc Soc Exp Biol Med. 107: 799-802. PMID: 13903844
  3. Fludrocortisone therapy in cerebral salt wasting.  |  Taplin, CE., et al. 2006. Pediatrics. 118: e1904-8. PMID: 17101713
  4. Therapies for adrenal insufficiency.  |  Oki, K. and Yamane, K. 2007. Expert Opin Pharmacother. 8: 1283-91. PMID: 17563263
  5. Low dose combination steroids control autoimmune mouse hearing loss.  |  Trune, DR. and Kempton, JB. 2010. J Neuroimmunol. 229: 140-5. PMID: 20800906
  6. Experimental cardiac hypertrophy induced by oral administration of mineralocorticoid and saline in rats.  |  Voucharas, C., et al. 2012. Angiology. 63: 416-9. PMID: 22007030
  7. Corticosteroid Fludrocortisone Acetate Targets Multiple End Points in Zebrafish (Danio rerio) at Low Concentrations.  |  Zhao, Y., et al. 2016. Environ Sci Technol. 50: 10245-54. PMID: 27618422
  8. The selective mineralocorticoid receptor modulator AZD9977 reveals differences in mineralocorticoid effects of aldosterone and fludrocortisone.  |  Bamberg, K., et al. 2019. J Renin Angiotensin Aldosterone Syst. 20: 1470320319827449. PMID: 30813831
  9. Treatment of Postural Orthostatic Tachycardia Syndrome With Medication: A Systematic Review.  |  Hasan, B., et al. 2020. J Child Neurol. 35: 1004-1016. PMID: 32838632
  10. Effects of low-dose hydrocortisone and hydrocortisone plus fludrocortisone in adults with septic shock: a protocol for a systematic review and meta-analysis of individual participant data.  |  Annane, D., et al. 2020. BMJ Open. 10: e040931. PMID: 33268422
  11. Evidence for fludrocortisone in postural hypotension.  |  . 2021. Drug Ther Bull. 59: 183. PMID: 34758971
  12. Stability Studies of Fludrocortisone Acetate Capsules and Fludrocortisone Acetate Titrated Powders (Powder Triturates).  |  Brandin, T., et al. 2022. Int J Pharm Compd. 26: 150-154. PMID: 35413013
  13. Renin and electrolytes indicate the mineralocorticoid activity of fludrocortisone: a 6 year study in primary adrenal insufficiency.  |  Ceccato, F., et al. 2023. J Endocrinol Invest. 46: 111-122. PMID: 35947299
  14. Fludrocortisone evaluation in aneurysmal subarachnoid hemorrhage patients with cerebral salt wasting (Flush Salt).  |  Elledge, SR., et al. 2023. Clin Neurol Neurosurg. 225: 107568. PMID: 36608470

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fludrocortisone, 50 mg

sc-207690
50 mg
$454.00