Molecular structure of Fludarabine phosphate
Fludarabine phosphate (CAS 75607-67-9)
Alternate Names:
9-beta-D-Arabinofuranosyl-2-fluoroadenine-5′-monophosphate; Fludara
CAS Number:
75607-67-9
Purity:
≥98%
Molecular Weight:
365.21
Molecular Formula:
C10H13FN5O7P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Fludarabine phosphate is a purine analog that functions as an antimetabolite. It inhibits DNA synthesis by interfering with the activity of DNA polymerase and ribonucleotide reductase, leading to the disruption of DNA replication and repair. Fludarabine phosphateis phosphorylated intracellularly to its active triphosphate form, which is incorporated into the DNA during replication, causing chain termination. Fludarabine phosphate induces apoptosis in lymphoid cells by activating caspase enzymes and disrupting mitochondrial function. Its mode of action involves the inhibition of RNA and protein synthesis, leading to the suppression of cell proliferation. it interferes with the function of certain enzymes involved in nucleic acid metabolism, ultimately leading to cell death.
Fludarabine phosphate (CAS 75607-67-9) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fludarabine phosphate, 5 mg | sc-491889 | 5 mg | $63.00 |