Date published: 2025-10-16

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Flocoumafen (CAS 90035-08-8)

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Alternate Names:
Flocoumafene
Application:
Flocoumafen is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type
CAS Number:
90035-08-8
Purity:
≥98%
Molecular Weight:
542.54
Molecular Formula:
C33H25F3O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Flocoumafen is an anticoagulant compound widely used in the study of coagulation processes and rodent pest control research. Due to its potent inhibition of the vitamin K epoxide reductase complex, it is a subject of interest in biochemistry for understanding the pathway of vitamin K recycling and its role in blood coagulation. Researchers may also investigate the environmental impact of Flocoumafen, particularly its persistence and effects on non-target organisms, as part of ecological and wildlife management studies. Additionally, Flocoumafen is utilized in research focused on the resistance mechanisms that rodents develop, which has implications for managing rodent populations effectively. The compound serves as a tool for studying the genetic factors that contribute to resistance and the spread of such traits through rodent populations.


Flocoumafen (CAS 90035-08-8) References

  1. Anticoagulant rodenticides.  |  Watt, BE., et al. 2005. Toxicol Rev. 24: 259-69. PMID: 16499407
  2. High-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry for the determination of flocoumafen and brodifacoum in whole blood.  |  Jin, MC., et al. 2007. J Appl Toxicol. 27: 18-24. PMID: 17177169
  3. Acquired coagulopathy caused by intoxication with the superwarfarin-type anticoagulant rodenticide flocoumafen.  |  Boettcher, S., et al. 2011. Eur J Haematol. 86: 173-5. PMID: 21059104
  4. The occurrence of second generation anticoagulant rodenticides in non-target raptor species in Norway.  |  Langford, KH., et al. 2013. Sci Total Environ. 450-451: 205-8. PMID: 23500818
  5. Comparative performance-based studies of second generation anticoagulant rodenticides bromadiolone and flocoumafen in Mus musculus.  |  Iqbal, A., et al. 2019. J Biol Regul Homeost Agents. 34: PMID: 31845562
  6. Elimination and accumulation of the rodenticide flocoumafen in rats following repeated oral administration.  |  Huckle, KR., et al. 1988. Xenobiotica. 18: 1465-79. PMID: 3245237
  7. Separation and Quantification of Superwarfarin Rodenticide Diastereomers-Bromadiolone, Difenacoum, Flocoumafen, Brodifacoum, and Difethialone-in Human Plasma.  |  Nosal, DG., et al. 2020. J AOAC Int. 103: 770-778. PMID: 33241367
  8. In Silico Analysis to Identify Molecular Targets for Chemicals of Concern: The Case Study of Flocoumafen, an Anticoagulant Pesticide.  |  Coronado-Posada, N., et al. 2021. Environ Toxicol Chem. 40: 2034-2043. PMID: 33729601
  9. Anticoagulant rodenticide blood-clotting dose-responses and resistance factors for Tyrosine139Cysteine (Y139C) heterozygous- and homozygous-resistant house mice (Mus musculus).  |  Baxter, MA., et al. 2022. Pest Manag Sci. 78: 4480-4487. PMID: 36181415
  10. Second-generation anticoagulant rodenticides in the blood of obligate and facultative European avian scavengers.  |  Oliva-Vidal, P., et al. 2022. Environ Pollut. 315: 120385. PMID: 36257565
  11. Field trials of flocoumafen against warfarin-resistant infestations of the Norway rat (Rattus norvegicus Berk.).  |  Buckle, AP. 1986. J Hyg (Lond). 96: 467-73. PMID: 3755451
  12. The susceptibility of Rattus rattus and Bandicota bengalensis to a new anticoagulant rodenticide, flocoumafen.  |  Parshad, VR. and Chopra, G. 1986. J Hyg (Lond). 96: 475-8. PMID: 3755452
  13. Pen and field trials of a new anticoagulant rodenticide flocoumafen against the house mouse (Mus musculus L.).  |  Rowe, FP., et al. 1985. J Hyg (Lond). 95: 623-7. PMID: 3841547

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Flocoumafen, 50 mg

sc-235141
50 mg
$194.00