FLJ11506 Antibody (D-6): sc-390860

FLJ11506 Antibody (D-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects the FLJ11506 protein of human origin, the 2310007F21Rik protein of mouse origin, and the corresponding rat homolog by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-FLJ11506 antibody (D-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. FLJ11506 protein plays a role in cellular processes, although exact functions remain to be fully elucidated. Understanding FLJ11506 function is crucial, as FLJ11506 may be involved in critical pathways affecting cellular signaling and homeostasis, potentially linking to various diseases when dysregulated. Chromosome 15, where FLJ11506 gene is located, encodes over 700 genes and is associated with several genetic disorders, including Angelman and Prader-Willi syndromes, which arise from deletions or mutations in the 15q11-q13 region. FLJ11506 gene product has been provisionally designated FLJ11506 pending further characterization, and ongoing research may reveal significance in health and disease, making FLJ11506 (D-6) antibody an essential tool for researchers studying this intriguing protein.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

FLJ11506 Antibody (D-6) References:

1. A p34(cdc2) survival checkpoint in cancer.  |  O'Connor, DS., et al. 2002. Cancer Cell. 2: 43-54. PMID: 12150824
2. Analysis of the DNA sequence and duplication history of human chromosome 15.  |  Zody, MC., et al. 2006. Nature. 440: 671-5. PMID: 16572171
3. Effective gene therapy in an authentic model of Tay-Sachs-related diseases.  |  Cachón-González, MB., et al. 2006. Proc Natl Acad Sci U S A. 103: 10373-10378. PMID: 16801539
4. Pyrimethamine as a potential pharmacological chaperone for late-onset forms of GM2 gangliosidosis.  |  Maegawa, GH., et al. 2007. J Biol Chem. 282: 9150-61. PMID: 17237499
5. Molecular epigenetics of Angelman syndrome.  |  Lalande, M. and Calciano, MA. 2007. Cell Mol Life Sci. 64: 947-60. PMID: 17347796
6. [The Prader-Willi syndrome].  |  Diene, G., et al. 2007. Ann Endocrinol (Paris). 68: 129-37. PMID: 17499572
7. Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromes.  |  Makoff, AJ. and Flomen, RH. 2007. Genome Biol. 8: R114. PMID: 17573966
8. Fibrillin-rich microfibrils: Structural determinants of morphogenetic and homeostatic events.  |  Ramirez, F. and Dietz, HC. 2007. J Cell Physiol. 213: 326-30. PMID: 17708531
9. Extracellular control of TGFbeta signalling in vascular development and disease.  |  ten Dijke, P. and Arthur, HM. 2007. Nat Rev Mol Cell Biol. 8: 857-69. PMID: 17895899
10. p34 (SEI-1) inhibits ROS-induced cell death through suppression of ASK1.  |  Hong, SW., et al. 2011. Cancer Biol Ther. 12: 421-6. PMID: 21725208
11. p34 is a novel regulator of the oncogenic behavior of NEDD4-1 and PTEN.  |  Hong, SW., et al. 2014. Cell Death Differ. 21: 146-60. PMID: 24141722
12. Premature ovarian failure with 46,XX,t(1;4)(p34.1;q34): first case report and literature review.  |  Vichinsartvichai, P., et al. 2015. Climacteric. 18: 656-8. PMID: 25427618

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FLJ11506 Antibody (D-6) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-FLJ11506 Antibody (D-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FLJ11506 Antibody (D-6) Specifications

Alternate Product Name: FLJ11506

Product Clone Name: D-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 293-308

Epitope Target: FLJ11506

Epitope Species: human

Product Reactivity/Detection: FLJ11506 of human origin, 2310007F21Rik of mouse origin and the corresponding rat homolog

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: equine, canine, bovine, porcine and avian

Additional Non-Mammalian Reactivity: avian

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for FLJ11506 Antibody (D-6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin