Flavone CAS: 525-82-6
MF: C15H10O2
MW: 222.24
A potentially useful biochemical for cytochrome P450 studies.

Flavone (CAS 525-82-6)

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Application: Flavone is a potentially useful biochemical for cytochrome P450 studies
CAS Number: 525-82-6
Molecular Weight: 222.24
Molecular Formula: C15H10O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Flavone has effects on CYP (P450) activity which are enzymes that metabolize most drugs in the body.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (partly), acetone (25 mg/ml), methanol, alcohol, and chloroform.
Storage :
Store at 4° C
Melting Point :
94-97° C (lit.)
Boiling Point :
185° C (lit.) at 1 mmHg
Density :
~1.2 g/cm3 (Predicted)
Refractive Index :
n20D 1.64 (Predicted)
IC50 :
Plasmodium falciparum: IC50 = 2 nM; CYP19: IC50 = 8 nM (human); Tankyrase-2: IC50 = 140 nM (human); Tankyrase-1: IC50 = 320 nM (human); RAW264.7: IC50 = 500 nM (mouse)
Ki Data :
GABA-A receptor; anion channel: Ki= 17 nM (human); GABA-A receptor; anion channel: Ki= 1 µM (rat); CA I: Ki= 1.88 µM (human); Adenosine A1 receptor: Ki= 3.28 µM (rat); Adenosine A2 receptor: Ki= 3.45 µM (rat)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
2
RTECS :
DJ3100630
PubChem CID :
10680
Merck Index :
14: 4092
MDL Number :
MFCD00006825
EC Number :
208-383-8
Beilstein Registry :
157598
SMILES :
C1=CC=C(C=C1)C2=CC(=O)C3=CC=CC=C3O2

Download SDS (MSDS)

Certificate of Analysis

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