MF: C15H10O2 MW: 222.24 A potentially useful biochemical for cytochrome P450 studies.
Flavone (CAS 525-82-6)
Flavone is a potentially useful biochemical for cytochrome P450 studies
C 15H 10O 2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. *
Certificate of Analysis for lot specific data (including water content).
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Flavone has effects on CYP (P450) activity which are enzymes that metabolize most drugs in the body.
Soluble in water (partly), acetone (25 mg/ml), methanol, alcohol, and chloroform.
94-97° C (lit.)
185° C (lit.) at 1 mmHg
20 D 1.64 (Predicted)
Plasmodium falciparum: IC
50 = 2 nM; CYP19: IC 50 = 8 nM (human); Tankyrase-2: IC 50 = 140 nM (human); Tankyrase-1: IC 50 = 320 nM (human); RAW264.7: IC 50 = 500 nM (mouse)
GABA-A receptor; anion channel: K
i= 17 nM (human); GABA-A receptor; anion channel: K i= 1 µM (rat); CA I: K i= 1.88 µM (human); Adenosine A1 receptor: K i= 3.28 µM (rat); Adenosine A2 receptor: K i= 3.45 µM (rat)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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