Date published: 2025-10-5

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Filamin 1 Antibody (5): sc-135906

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Datasheets
  • Filamin 1 Antibody (5) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
  • raised against amino acids 2492-2647 of Filamin 1 of human origin
  • recommended for detection of Filamin 1 of human origin by WB, IP and IF; not recommended for IP
  • See Filamin 1 (E-3): sc-17749 for Filamin 1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Filamin 1 Antibody (5). This work is in progress.

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    Filamin 1 Antibody (5) is a mouse monoclonal IgG1 antibody that detects Filamin 1 in human samples through western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Filamin 1 is a crucial actin-binding protein that plays a significant role in maintaining the structural integrity of the cytoskeleton by crosslinking actin filaments into a three-dimensional network. This network is essential for various cellular processes, including maintaining cell shape, enabling cell motility, and facilitating intracellular transport. Anti-Filamin 1 antibody (5) helps researchers study cellular signaling pathways and mechanotransduction, where Filamin 1 helps cells respond to mechanical stimuli. Filamin 1 interacts with several other proteins, including integrins and various signaling molecules, which further underscores its role in cellular architecture and function. Filamin 1′s ability to form homodimers enhances its capacity to stabilize actin structures, making Filamin 1 a vital component in both muscle and non-muscle tissues. With diverse functions and interactions, Filamin 1 monoclonal antibody (5) provides a valuable tool for researchers studying these critical processes.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Filamin 1 Antibody (5)

    sc-135906
    50 µg/0.5 ml
    $316.00

    What is the recommended fixation method for immunofluorescence staining with Filamin 1 (5): sc-135906 monoclonal antibody?

    Asked by: AbPolly
    Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10ºC methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
    Answered by: Technical Support
    Date published: 2017-03-24
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    Rated 4 out of 5 by from Robust band in western blot analysis of humanRobust band in western blot analysis of human endothelial tissue extract. -SCBT QC
    Date published: 2014-09-19
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    Filamin 1 Antibody (5) is rated 4.0 out of 5 by 1.
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