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Fibronectin Antibody (Fn-4) is a mouse monoclonal IgG1 antibody that detects Fibronectin in human samples through western blotting (WB) and immunoprecipitation (IP) applications. Fibronectin is a crucial extracellular matrix glycoprotein that plays a significant role in various biological processes, including cell adhesion, motility, and wound healing. Anti-Fibronectin antibody (Fn-4) recognizes a high molecular weight heterodimeric structure that interacts with cell surface receptors and other extracellular matrix components, facilitating cellular communication and structural integrity. Fibronectin is found in the extracellular matrix, where Fibronectin contributes to tissue repair and regeneration. Fibronectin′s presence at injury sites is vital for recruiting cells necessary for healing, providing a scaffold for cell attachment and migration. Alternative splicing and post-translational modifications, such as glycosylation, lead to different Fibronectin isoforms, some associated with specific tissue types or pathological conditions, including malignancies. Fibronectin (Fn-4) monoclonal antibody serves as an essential tool for researchers studying these complex interactions and Fibronectin′s role in health and disease.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fibronectin Antibody (Fn-4) | sc-53286 | 200 µg/ml | $316.00 |