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Fibronectin Antibody (617) is a mouse monoclonal IgG1 antibody that detects Fibronectin in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Fibronectin is a crucial extracellular matrix glycoprotein that plays a significant role in cell adhesion, motility, and wound healing, making Fibronectin essential for tissue repair and regeneration. This high molecular weight heterodimeric protein maintains structural integrity of tissues while facilitating cellular interactions and signaling pathways vital for normal physiological functions. Fibronectin′s ability to undergo alternative splicing and glycosylation results in various isoforms, some associated with specific tissues or pathological conditions, such as malignancies. Notably, glycosylated Fibronectin and splice variants have been linked to myofibroblast phenotype formation in Dupuytren′s disease, highlighting Fibronectin′s importance in both health and disease. Anti-Fibronectin antibody (617) serves as an invaluable tool for researchers studying extracellular matrix component dynamics and their implications in various biological processes.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fibronectin Antibody (617) | sc-81769 | 200 µg/ml | $316.00 | |||
Fibronectin Antibody (617): m-IgG1 BP-HRP Bundle | sc-542630 | 200 µg Ab; 20 µg BP | $354.00 |