Fibroblast Marker Antibody (ER-TR7): sc-73355

Fibroblast Marker Antibody (ER-TR7) is a rat monoclonal IgG2a antibody that detects Fibroblast Marker in mouse, rat, and human samples by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Fibroblast Marker (ER-TR7) antibody is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Fibroblasts play a crucial role in synthesizing and maintaining the extracellular matrix, which is essential for tissue integrity and repair. These cells produce key components such as collagens, glycosaminoglycans, and glycoproteins, which provide structural support and facilitate wound healing. The dynamic nature of fibroblasts allows adaptation to various tissue environments, and their proliferative capacity makes them valuable models in biological research. Additionally, the expression of intermediate filament proteins like Vimentin serves as a marker for identifying fibroblasts and understanding their mesodermal origin. Fibroblast Marker (ER-TR7) monoclonal antibody advances research on fibroblast biology, enabling scientists to explore diverse functions and interactions within the extracellular matrix.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Fibroblast Marker Antibody (ER-TR7) References:

1. Expression, purification, and kinetic characterization of full-length human fibroblast activation protein.  |  Sun, S., et al. 2002. Protein Expr Purif. 24: 274-81. PMID: 11858723
2. Human fibroblast migration in three-dimensional collagen gel in response to noninvasive electrical stimulus. I. Characterization of induced three-dimensional cell movement.  |  Sun, S., et al. 2004. Tissue Eng. 10: 1548-57. PMID: 15588414
3. Molecular characterization of the cytotoxic mechanism of multiwall carbon nanotubes and nano-onions on human skin fibroblast.  |  Ding, L., et al. 2005. Nano Lett. 5: 2448-64. PMID: 16351195
4. High-level expression of basic fibroblast growth factor in transgenic soybean seeds and characterization of its biological activity.  |  Ding, SH., et al. 2006. Biotechnol Lett. 28: 869-75. PMID: 16786271
5. Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions.  |  Hou, T., et al. 2006. J Biomater Sci Polym Ed. 17: 735-46. PMID: 16909942
6. Characterization of fibroblast morphology on bioactive surfaces using vertical scanning interferometry.  |  Revell, CM., et al. 2006. Matrix Biol. 25: 523-33. PMID: 16962756
7. Free radical scavenging effect of Pu-erh tea extracts and their protective effect on oxidative damage in human fibroblast cells.  |  Jie, G., et al. 2006. J Agric Food Chem. 54: 8058-64. PMID: 17032009
8. Identification and characterization of a fibroblast marker: FSP1.  |  Strutz, F., et al. 1995. J Cell Biol. 130: 393-405. PMID: 7615639
9. Influence of myosin II activity on stiffness of fibroblast cells.  |  Schäfer, A. and Radmacher, M. 2005. Acta Biomater. 1: 273-80. PMID: 16701806

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Fibroblast Marker Antibody (ER-TR7) has 105 citations in a variety of scientific publications.

Primary antibodies like Anti-Fibroblast Marker Antibody (ER-TR7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Fibroblast Marker Antibody (ER-TR7) Specifications

Alternate Product Name: Fibroblast Marker

Product Clone Name: ER-TR7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2a

Amino Acids:

Epitope Target: Fibroblast Marker

Epitope Species: mouse

Product Reactivity/Detection: reticular fibroblasts

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, FCM

Vialing Information: Each vial contains 200 µg IgG_2a in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 105 citations in various scientific publications

Available Conjugates/Forms for Fibroblast Marker Antibody (ER-TR7): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin