FGF-19 Antibody (W12): sc-73984
- FGF-19 Antibody (W12) is a mouse monoclonal IgG1, cited in 5 publications, provided at 100 µg/ml
- raised against full length recombinant FGF-19 of human origin
- recommended for detection of FGF-19 of human origin by WB, IP, IF, IHC(P) and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FGF-19 Antibody (W12). This work is in progress.
FGF-19 Antibody (W12) is a mouse monoclonal IgG1 antibody that detects FGF-19 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). FGF-19 is a member of the fibroblast growth factor (FGF) family, which plays a crucial role in regulating cellular processes such as proliferation, differentiation, and survival. FGF-19 is involved in metabolic regulation and influences bile acid synthesis and glucose metabolism, making FGF-19 an important factor in maintaining metabolic homeostasis. FGF-19 is primarily expressed in the liver and intestine, where FGF-19 acts as a signaling molecule that interacts with fibroblast growth factor receptors (FGFRs) to mediate biological effects. Understanding FGF-19 function is vital, as dysregulation of FGF-19 signaling pathway has been implicated in various metabolic disorders, including obesity and diabetes. Anti-FGF-19 antibody (W12) provides a reliable tool for researchers aiming to explore the role of FGF-19 in health and disease.
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FGF-19 Antibody (W12) References:
- Laparoscopic sleeve gastrectomy differentially affects serum concentrations of FGF-19 and FGF-21 in morbidly obese subjects. | Haluzíková, D., et al. 2013. Obesity (Silver Spring). 21: 1335-42. PMID: 23670968
- Short-term and divergent regulation of FGF-19 and FGF-21 during oral lipid tolerance test but not oral glucose tolerance test. | Schmid, A., et al. 2015. Exp Clin Endocrinol Diabetes. 123: 88-94. PMID: 25654672
- Impact of gut hormone FGF-19 on type-2 diabetes and mitochondrial recovery in a prospective study of obese diabetic women undergoing bariatric surgery. | Martinez de la Escalera, L., et al. 2017. BMC Med. 15: 34. PMID: 28202005
- Evaluation of FGF-19 and β-klotho as biomarkers in patients with intrahepatic cholestasis of pregnancy. | Tayyar, AT., et al. 2019. Arch Med Sci. 15: 113-119. PMID: 30697260
- Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia. | Mulla, CM., et al. 2019. Obes Surg. 29: 2092-2099. PMID: 30976983
- Effect of bariatric surgery on circulating FGF-19: A systematic review and meta-analysis. | Ryan, PM., et al. 2020. Obes Rev. 21: e13038. PMID: 32329176
- Association of FGF-19 and FGF-21 levels with primary sarcopenia. | Bag Soytas, R., et al. 2021. Geriatr Gerontol Int. 21: 959-962. PMID: 34405516
- Serum Glucagon, Bile Acids, and FGF-19: Metabolic Behavior Patterns After Roux-en-Y Gastric Bypass and Vertical Sleeve Gastrectomy. | Yang, C., et al. 2021. Obes Surg. 31: 4939-4946. PMID: 34471996
- The effectiveness of small heterodimer partner and FGF 19 levels in prediction of perinatal morbidity in intrahepatic cholestasis of pregnancy. | Bayram, M., et al. 2022. J Obstet Gynaecol. 42: 1174-1178. PMID: 35156505
- Adiponectin, A-FABP and FGF-19 Levels in Women with Early Diagnosed Gestational Diabetes. | Karasek, D., et al. 2022. J Clin Med. 11: PMID: 35566542
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FGF-19 Antibody (W12) | sc-73984 | 100 µg/ml | $316.00 |