Date published: 2026-5-3

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Ferric citrate (CAS 334024-15-6)

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Alternate Names:
Iron(III) citrate
CAS Number:
334024-15-6
Molecular Weight:
244.94
Molecular Formula:
C6H5FeO7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ferric citrate is a chemical compound that functions as a metal chelator in experimental applications. It acts by binding to metal ions, particularly iron, in a process known as chelation. This chelation process involves the formation of multiple bonds between the ferric citrate molecule and the metal ion, effectively sequestering the metal and preventing its participation in other chemical reactions. This mechanism of action allows ferric citrate to be used in experimental to control the availability and reactivity of metal ions in various systems. By chelating metal ions, ferric citrate may influence the behavior of biological molecules and processes that are dependent on metal ion interactions, providing insights into the role of metal ions in biochemical and physiological pathways. In this way, ferric citrate served for investigating the impact of metal ion availability on cellular and molecular processes, contributing to a deeper understanding of metal ion homeostasis and function in biological systems.


Ferric citrate (CAS 334024-15-6) References

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  2. Ferric Citrate in Patients With Chronic Kidney Disease.  |  Block, GA. 2016. Semin Nephrol. 36: 130-5. PMID: 27236135
  3. Characterization of ferroptosis in murine models of hemochromatosis.  |  Wang, H., et al. 2017. Hepatology. 66: 449-465. PMID: 28195347
  4. Ferric citrate: a novel phosphate-binding agent.  |  Umanath, K., et al. 2013. Expert Rev Endocrinol Metab. 8: 13-19. PMID: 30731649
  5. Mechanism of Action and Clinical Attributes of Auryxia® (Ferric Citrate).  |  Ganz, T., et al. 2019. Drugs. 79: 957-968. PMID: 31134521
  6. Ferric citrate: cardio- and renoprotective in chronic kidney disease?  |  Hanudel, MR. 2019. Kidney Int. 96: 1277-1279. PMID: 31759486
  7. Ferric citrate in the management of hyperphosphataemia and iron deficiency anaemia: A meta-analysis in patients with chronic kidney disease.  |  Choi, YJ., et al. 2021. Br J Clin Pharmacol. 87: 414-426. PMID: 32470149
  8. Enteral ferric citrate absorption is dependent on the iron transport protein ferroportin.  |  Hanudel, MR., et al. 2022. Kidney Int. 101: 711-719. PMID: 34838540
  9. A review of ferric citrate clinical studies, and the rationale and design of the Ferric Citrate and Chronic Kidney Disease in Children (FIT4KiD) trial.  |  Hanudel, MR., et al. 2022. Pediatr Nephrol. 37: 2547-2557. PMID: 35237863
  10. The ins and outs of ferric citrate.  |  Haase, VH. 2022. Kidney Int. 101: 668-670. PMID: 35314048
  11. Renoprotective effects of ferric citrate in a mouse model of chronic kidney disease.  |  Hanudel, MR., et al. 2022. Sci Rep. 12: 6695. PMID: 35461329
  12. Ferric Citrate Uptake Is a Virulence Factor in Uropathogenic Escherichia coli.  |  Frick-Cheng, AE., et al. 2022. mBio. 13: e0103522. PMID: 35546538
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ferric citrate, 250 g

sc-235134
250 g
$59.00