Molecular structure of Fenoldopam monohydrobromide, CAS Number: 67287-54-1
Fenoldopam monohydrobromide (CAS 67287-54-1)
Alternate Names:
SKF-8252; 6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol monohydrobromide
CAS Number:
67287-54-1
Purity:
≥98%
Molecular Weight:
386.67
Molecular Formula:
C16H16ClNO3 HBr
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A selective dopamine agonist that is being considered for the parenteral treatment of systemic hypertension. In both an oral and parenteral form, this compound causes peripheral vasodilation by stimulating dopamine-1 adrenergic receptors. Intravenous fenoldopam may provide advantages over sodium nitroprusside because it can induce both a diuresis and natriuresis. It is not light sensitive, nor is it associated with cyanide toxicity. There is no evidence for rebound hypertension after discontinuation of fenoldopam infusion.
Fenoldopam monohydrobromide (CAS 67287-54-1) References
Hahn, R.A., et al., Characterization of the peripheral and central effects of SK&F 82526a novel dopamine receptor agonist. J. Pharmacol. Exp. Ther. 223, 305-313, (1982) Hussain, T., and Lokhandwala, M.F., Renal dopamine DA1 receptor coupling with G(S) and G(q/11) proteins in spontaneously hypertensive rats. Am. J. Physiol. 272, F339-F346, (1997) Venkatakrishnan, U., et al., The role of intrarenal nitric oxide in the natriuretic response to dopamine-receptor activation. Clin. Exp. Hypertens. 22, 309-324, (2000) Quevedo, M., et al., The effect of fenoldopam on the blood pressure of the rat. Gen. Pharmacol. 32, 123-125, (1999) deVries, P.A., et al., Impaired renal vascular response to a D1-like receptor agonist but not to an ACE inhibitor in conscious spontaneously hypertensive rats. J. Cardiovasc. Pharmacol. 34, 191-198, (1999)Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fenoldopam monohydrobromide, 5 mg | sc-215032 | 5 mg | $175.00 | |||
Fenoldopam monohydrobromide, 25 mg | sc-215032A | 25 mg | $375.00 |