Date published: 2026-2-7

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Felypressin Acetate (CAS 914453-97-7)

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Alternate Names:
2-L-Phenylalanine-8-L-lysinevasopressin Acetate (Salt); 2,3-Bis(phenylalanine)-8-lysineoxytocin Acetate; 2-(Phenylalanine)-8-lysinevasopressin Acetate
Application:
Felypressin Acetate is an activator of AVP Receptor V1a.
CAS Number:
914453-97-7
Molecular Weight:
1040.22
Molecular Formula:
C46H65N13O11S2•xC2H4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Felypressin Acetate is an activator of AVP Receptor V1a.


Felypressin Acetate (CAS 914453-97-7) References

  1. Clinically safe dosage of felypressin for patients with essential hypertension.  |  Sunada, K., et al. 1996. Anesth Prog. 43: 108-15. PMID: 10323116
  2. Felypressin-induced reduction in coronary blood flow and myocardial tissue oxygen tension during anesthesia in dogs.  |  Agata, H., et al. 1999. Can J Anaesth. 46: 1070-5. PMID: 10566930
  3. A comparison of the side effects of prilocaine with felypressin and lignocaine with adrenaline in large loop excision of the transformation zone of the cervix: results of a randomised trial.  |  Howells, RE., et al. 2000. BJOG. 107: 28-32. PMID: 10645858
  4. Acute toxicity (LD50 and CD50) of lidocaine and prilocaine in combination with adrenaline and felypressin.  |  Volpato, MC., et al. 1999. Indian J Dent Res. 10: 138-44. PMID: 10865397
  5. Adenosine and amrinone reverse felypressin-induced depression of myocardial tissue oxygen tension in dogs.  |  Kasahara, M., et al. 2000. Can J Anaesth. 47: 1107-13. PMID: 11097542
  6. Effects of local injection of prilocaine-felypressin on the myocardial oxygen balance in dogs.  |  Miyachi, K., et al. 2003. Eur J Oral Sci. 111: 339-45. PMID: 12887400
  7. Quality specifications for peptide drugs: a regulatory-pharmaceutical approach.  |  Vergote, V., et al. 2009. J Pept Sci. 15: 697-710. PMID: 19750489
  8. Felypressin, but not epinephrine, reduces myocardial oxygen tension after an injection of dental local anesthetic solution at routine doses.  |  Inagawa, M., et al. 2010. J Oral Maxillofac Surg. 68: 1013-7. PMID: 20031290
  9. Felypressin increases blood pressure during dental procedures in hypertensive patients.  |  Bronzo, AL., et al. 2012. Arq Bras Cardiol. 99: 724-31. PMID: 22735869
  10. Comparison of epinephrine and felypressin pressure effects in 1K1C hypertensive rats treated or not with atenolol.  |  Fleury, CA., et al. 2015. J Anesth. 29: 56-64. PMID: 24962945
  11. Peptide-based therapeutics: quality specifications, regulatory considerations, and prospects.  |  Rastogi, S., et al. 2019. Drug Discov Today. 24: 148-162. PMID: 30296551
  12. Increase in pulse pressure on administration of a dental local anesthetic solution, prilocaine hydrochloride with felypressin in male diabetic patients with coronary heart disease.  |  Kubota, K., et al. 2020. Clin Oral Investig. 24: 239-246. PMID: 31079247
  13. Difference in the Effects of Lidocaine With Epinephrine and Prilocaine With Felypressin on the Autonomic Nervous System During Extraction of the Impacted Mandibular Third Molar: A Randomized Controlled Trial.  |  Yamashita, K., et al. 2020. J Oral Maxillofac Surg. 78: 215.e1-215.e8. PMID: 31654643
  14. Effects of noradrenaline and felypressin on cutaneous local blood flow after sympathetic denervation. A study on rats.  |  Norberg, KA. and Palmer, B. 1972. Scand J Plast Reconstr Surg. 6: 106-9. PMID: 4652231
  15. Cardiac effects of adrenaline and felypressin as vasoconstrictors in local anaesthesia for oral surgery under diazepam sedation.  |  Aellig, WH., et al. 1970. Br J Anaesth. 42: 174-6. PMID: 5440531

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Felypressin Acetate, 5 mg

sc-497815
5 mg
$380.00