Date published: 2025-12-24

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FeLV p15e Antibody (PF6J-2A1): sc-65622

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Datasheets
  • FeLV p15e Antibody (PF6J-2A1) is a mouse monoclonal IgG2a provided at 100 µg/ml
  • raised against FeLV p15e
  • recommended for detection of Env p15e transmembrane of FeLV origin by WB, IP, IF and IHC(P)
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FeLV p15e Antibody (PF6J-2A1). This work is in progress.

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    FeLV p15e Antibody (PF6J-2A1) is a mouse monoclonal IgG antibody that detects p15E protein of Feline leukemia virus (FeLV) by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry with paraffin-embedded sections (IHCP). Anti-p15E antibody (PF6J-2A1) specifically targets p15E protein, a crucial transmembrane envelope protein that induces neutralizing antibodies in infected cats. p15E monoclonal antibody (PF6J-2A1) recognizes a protein essential for vaccine development against FeLV, a major health concern for feline populations. p15E (PF6J-2A1) antibody targets a surface protein that facilitates host cell interaction and contributes to immune response evasion. Understanding p15E protein dynamics and interactions helps researchers develop effective therapeutic strategies and vaccines to combat FeLV, improving health outcomes for affected cats.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    FeLV p15e Antibody (PF6J-2A1) References:

    1. Antibodies neutralizing feline leukaemia virus (FeLV) in cats immunized with the transmembrane envelope protein p15E.  |  Langhammer, S., et al. 2006. Immunology. 117: 229-37. PMID: 16423059
    2. Inhibition of phorbol ester-induced neutrophil chemiluminescence by FeLV.  |  Dezzutti, CS., et al. 1990. Arch Virol. 111: 75-85. PMID: 2158290
    3. Novel neutralising antibodies targeting the N-terminal helical region of the transmembrane envelope protein p15E of the porcine endogenous retrovirus (PERV).  |  Waechter, A. and Denner, J. 2014. Immunol Res. 58: 9-19. PMID: 23729215
    4. A targeted mutation within the feline leukemia virus (FeLV) envelope protein immunosuppressive domain to improve a canarypox virus-vectored FeLV vaccine.  |  Schlecht-Louf, G., et al. 2014. J Virol. 88: 992-1001. PMID: 24198407
    5. Feline leukemia virus: current status of the feline induced immune depression and immunoprevention.  |  Olsen, RG., et al. 1987. Cancer Metastasis Rev. 6: 243-60. PMID: 2826030
    6. The reversal of feline retroviral-induced suppression of lymphocyte Con A receptor mobility by indomethacin and PGE2.  |  Lewis, MG., et al. 1985. Leuk Res. 9: 1105-9. PMID: 2999519
    7. Reversal of feline retroviral suppression by indomethacin.  |  Lewis, MG., et al. 1985. Leuk Res. 9: 1451-6. PMID: 3001436
    8. Suppression of in vitro neutrophil function by feline leukaemia virus (FeLV) and purified FeLV-p15E.  |  Lafrado, LJ., et al. 1987. J Gen Virol. 68 (Pt 2): 507-13. PMID: 3029288
    9. [Feline leukemia virus infection - a guide to diagnosis].  |  Giselbrecht, J., et al. 2022. Tierarztl Prax Ausg K Kleintiere Heimtiere. 50: 198-212. PMID: 35790167
    10. Field Performance of a Rapid Test to Detect Progressive, Regressive, and Abortive Feline Leukemia Virus Infections in Domestic Cats in Australia and Germany.  |  Westman, ME., et al. 2023. Viruses. 15: PMID: 36851705

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    FeLV p15e Antibody (PF6J-2A1)

    sc-65622
    100 µg/ml
    $316.00