FcRH3 Antibody (A-12): sc-166347
- FcRH3 Antibody (A-12) is a mouse monoclonal IgM κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 631-660 near the C-terminus of FcRH3 of human origin
- recommended for detection of FcRH3 of human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for FcRH3 Antibody (A-12). This work is in progress.
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FcRH3 Antibody (A-12) is a mouse monoclonal IgM antibody that detects FcRH3 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FcRH3, a member of the Fc receptor homolog (FcRH) family, plays a crucial role in the regulation of the immune system, particularly in B cell development and function. FcRH3 is primarily expressed in mature B lineage cells, where FcRH3 contributes to the modulation of immune responses by containing immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain, which are essential for downregulating signaling pathways that could lead to excessive immune activation. The importance of FcRH3 is underscored by potential involvement in various autoimmune conditions, as mutations in the genes encoding FcRH proteins have been linked to systemic lupus erythematosus, autoimmune thyroid disease, and rheumatoid arthritis. Anti-FcRH3 antibody (A-12) enables researchers to gain valuable insights into the regulatory mechanisms of B cells and their implications in both normal physiology and disease states, making anti-FcRH3 antibody (A-12) an indispensable tool for studies in immunology and related fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FcRH3 Antibody (A-12) | sc-166347 | 200 µg/ml | $322.00 | |||
FcRH3 (A-12) Neutralizing Peptide | sc-166347 P | 100 µg/0.5 ml | $69.00 |