FBPase-1 Inhibitor is a cell-permeable benzoxazolo-sulfonamide compound that inhibits hFBPase-1 enzymatic activity by competing at the AMP allosteric binding site. FBPase-1 Inhibitor has been shown to block glucose production in starved rat hepatoma cells.
1. von Geldern, Thomas W., et al., 2006. Benzoxazole benzenesulfonamides are novel allosteric inhibitors of fructose-1,6-bisphosphatase with a distinct binding mode. Bioorganic & medicinal chemistry letters. 16(7): 1811-5. PMID: 16442285 2. Lai, Chunqiu., et al., 2006. Benzoxazole benzenesulfonamides as allosteric inhibitors of fructose-1,6-bisphosphatase. Bioorganic & medicinal chemistry letters. 16(7): 1807-10. PMID: 16446092
Soluble in DMSO
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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