Molecular structure of Fatostatin, CAS Number: 125256-00-0
Fatostatin (CAS 125256-00-0)
Alternate Names:
FATOSTATIN Fatostatin A 2-(2-propylpyridin-4-yl)-4-(p-tolyl)thiazole 4-(4-methylphenyl)-2-(2-propylpyridin-4-yl)-1,3-thiazole
CAS Number:
125256-00-0
Molecular Weight:
294.40
Molecular Formula:
C18H18N2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Fatostatin (CAS 125256-00-0) References
- Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma. | Cai, J., et al. 2023. Cell Death Dis. 14: 211. PMID: 36966152
- Cholesterol biosynthesis modulates differentiation in murine cranial neural crest cells. | Pascual, F., et al. 2023. Sci Rep. 13: 7073. PMID: 37127649
- Inhibition of the SREBP pathway prevents SARS-CoV-2 replication and inflammasome activation. | Soares, VC., et al. 2023. Life Sci Alliance. 6: PMID: 37669865
- Identification of the novel role of sterol regulatory element binding proteins (SREBPs) in mechanotransduction and intraocular pressure regulation. | Wang, T., et al. 2023. FASEB J. 37: e23248. PMID: 37823226
- Effect of FTY720P on lipid accumulation in HEPG2 cells. | Rida, R. and Kreydiyyeh, S. 2023. Sci Rep. 13: 19716. PMID: 37953311
- G protein-coupled estrogen receptor activates PI3K/AKT/mTOR signaling to suppress ferroptosis via SREBP1/SCD1-mediated lipogenesis. | Chen, J., et al. 2024. Mol Med. 30: 28. PMID: 38383297
- Targeting ABCG1 and SREBP-2 mediated cholesterol homeostasis ameliorates Zika virus-induced ocular pathology. | Singh, S., et al. 2024. iScience. 27: 109088. PMID: 38405605
- Sterol Regulatory Element Binding Protein 1: A Mediator for High-Fat Diet-Induced Hepatic Gluconeogenesis and Glucose Intolerance in Fish. | Zhao, Z., et al. 2024. J Nutr. 154: 1505-1516. PMID: 38460786
- Fatostatin promotes anti-tumor immunity by reducing SREBP2 mediated cholesterol metabolism in tumor-infiltrating T lymphocytes. | Zhu, L., et al. 2024. Eur J Pharmacol. 971: 176519. PMID: 38522641
- ADAM9 drives the immunosuppressive microenvironment by cholesterol biosynthesis-mediated activation of IL6-STAT3 signaling for lung tumor progression. | Liu, JP., et al. 2024. Am J Cancer Res. 14: 1850-1865. PMID: 38726266
Inhibitor of:
2410131K14Rik, ACCβ, cHMGCS, EG432995, NPC Marker, Perilipin, SCAP, SCD, SREB1, SREBP-1, and SREBP-2.Activator of:
CYP46.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Fatostatin, 100 mg | sc-507496 | 100 mg | $450.00 |