FAM153A/B Antibody (F-6): sc-514616

FAM153A/B Antibody (F-6) is a mouse monoclonal IgM antibody that detects FAM153A/B of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-FAM153A/B antibody (F-6) is available as the non-conjugated form. FAM153A and FAM153B proteins, consisting of 310 and 387 amino acids respectively, are encoded by genes located on human chromosome 5, which encompasses approximately 6% of the human genome and is associated with various genetic disorders. FAM153A/B proteins are believed to play a role in cellular signaling pathways, crucial for maintaining normal cellular functions and responses to environmental stimuli. Disruptions in these pathways can lead to developmental disorders and contribute to cancer pathogenesis. FAM153A/B proteins may interact with other cellular proteins, influencing processes such as cell proliferation and apoptosis, highlighting their importance in both health and disease. FAM153A/B (F-6) antibody serves as an essential tool for researchers investigating these critical biological processes and their implications in human health.

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FAM153A/B Antibody (F-6) References:

1. Duodenal adenomatosis in familial adenomatous polyposis coli. A review of the literature and results from the Heidelberg Polyposis Register.  |  Kadmon, M., et al. 2001. Int J Colorectal Dis. 16: 63-75. PMID: 11355321
2. The gene for Treacher Collins syndrome maps to the long arm of chromosome 5.  |  Dixon, MJ., et al. 1991. Am J Hum Genet. 49: 17-22. PMID: 1676560
3. Cockayne syndrome exhibits dysregulation of p21 and other gene products that may be independent of transcription-coupled repair.  |  Cleaver, JE., et al. 2007. Neuroscience. 145: 1300-8. PMID: 17055654
4. A new genomic mechanism leading to cri-du-chat syndrome.  |  South, ST., et al. 2006. Am J Med Genet A. 140: 2714-20. PMID: 17103439
5. Redefining monosomy 5 by molecular cytogenetics in 23 patients with MDS/AML.  |  Herry, A., et al. 2007. Eur J Haematol. 78: 457-67. PMID: 17391336
6. Somatic APC mosaicism: a frequent cause of familial adenomatous polyposis (FAP).  |  Aretz, S., et al. 2007. Hum Mutat. 28: 985-92. PMID: 17486639
7. Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p- syndrome.  |  Du, HY., et al. 2007. Aging Cell. 6: 689-97. PMID: 17875000
8. Molecular mechanisms of skin aging: state of the art.  |  Makrantonaki, E. and Zouboulis, CC. 2007. Ann N Y Acad Sci. 1119: 40-50. PMID: 18056953
9. Identifying a Deletion Affecting Total Lung Capacity Among Subjects in the COPDGene Study Cohort.  |  Begum, F., et al. 2016. Genet Epidemiol. 40: 81-8. PMID: 26643968
10. Family with sequence similarity 153 member B as a potential prognostic biomarker of gastric cancer.  |  Yang, Y., et al. 2022. Math Biosci Eng. 19: 12581-12600. PMID: 36654012
11. The fusiform gyrus exhibits differential gene-gene co-expression in Alzheimer's disease.  |  Ribeiro-Dos-Santos, A., et al. 2023. Front Aging Neurosci. 15: 1138336. PMID: 37255536
12. A physical map of 15 loci on human chromosome 5q23-q33 by two-color fluorescence in situ hybridization.  |  Saltman, DL., et al. 1993. Genomics. 16: 726-32. PMID: 8325647

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FAM153A/B Antibody (F-6) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-FAM153A/B Antibody (F-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FAM153A/B Antibody (F-6) Specifications

Alternate Product Name: FAM153A/B

Product Clone Name: F-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 36-59

Epitope Target: FAM153A

Epitope Species: human

Product Reactivity/Detection: FAM153A and FAM153B

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for FAM153A/B Antibody (F-6): P: Blocking Peptide