FAM110A Antibody (B-11): sc-376464

FAM110A Antibody (B-11) is a mouse monoclonal IgG3 kappa light chain antibody that detects FAM110A of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-FAM110A antibody (B-11) is available as non-conjugated. FAM110A, or family with sequence similarity 110, member A, is a 295 amino acid protein that plays a crucial role in cell cycle regulation, particularly during S phase and G2/M phase, where expression significantly increases. FAM110A localizes in the cytoplasm, cytoskeleton, and centrosome, colocalizing with microtubules during interphase and at spindle poles during mitosis, highlighting importance in maintaining proper cell division and ensuring genomic stability. The gene encoding FAM110A resides on human chromosome 20, a region containing over 60 genes implicated in various biological processes, including male fertility through genes essential for seminal production. FAM110A interacts with CSPP, further emphasizing a role in facilitating accurate cell cycle progression. FAM110A antibody (B-11) serves as an invaluable tool for researchers studying cell division dynamics and molecular mechanisms underlying various cellular processes.

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FAM110A Antibody (B-11) References:

1. Does PRNP gene control the clinical and pathological phenotype of human spongiform transmissible encephalopathies?  |  Masullo, C. and Macchi, G. 2001. Clin Neuropathol. 20: 19-25. PMID: 11220690
2. Gerstmann-Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies.  |  Collins, S., et al. 2001. J Clin Neurosci. 8: 387-97. PMID: 11535002
3. Early pattern of epilepsy in the ring chromosome 20 syndrome.  |  Ville, D., et al. 2006. Epilepsia. 47: 543-9. PMID: 16529619
4. Trisomy 20 mosaicism and nonmosaic trisomy 20: a report of 2 cases.  |  Joó, JG., et al. 2006. J Reprod Med. 51: 209-12. PMID: 16674019
5. Characterization of the FAM110 gene family.  |  Hauge, H., et al. 2007. Genomics. 90: 14-27. PMID: 17499476
6. Eppin: an epididymal protease inhibitor and a target for male contraception.  |  O'Rand, MG., et al. 2007. Soc Reprod Fertil Suppl. 63: 445-53. PMID: 17566290
7. A locus on chromosome 20 encompassing genes that are highly expressed in the epididymis.  |  Lundwall, A. 2007. Asian J Androl. 9: 540-4. PMID: 17589793
8. Ring chromosome 20 syndrome without deletions of the subtelomeric and CHRNA4--KCNQ2 genes loci.  |  Elghezal, H., et al. 2007. Eur J Med Genet. 50: 441-5. PMID: 17851150
9. Cellular pathways leading to neuronal dysfunction and degeneration.  |  Kazantsev, AG. 2007. Drug News Perspect. 20: 501-9. PMID: 18080037
10. The prion diseases.  |  Prusiner, SB. 1998. Brain Pathol. 8: 499-513. PMID: 9669700

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-FAM110A Antibody (B-11) has 2 citations in a variety of scientific publications.

Primary antibodies like Anti-FAM110A Antibody (B-11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

FAM110A Antibody (B-11) Specifications

Alternate Product Name: FAM110A

Product Clone Name: B-11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₃ kappa light chain

Amino Acids: 103-139

Epitope Target: FAM110A

Epitope Species: human

Product Reactivity/Detection: FAM110A

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₃ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 2 citations in various scientific publications

Available Conjugates/Forms for FAM110A Antibody (B-11): P: Blocking Peptide