Factor XIII B Antibody (GMA-033): sc-65957

Factor XIII B Antibody (GMA-033) is a mouse monoclonal IgG1 antibody that detects Factor XIII B protein of human origin by western blotting (WB). Anti-Factor XIII B antibody (GMA-033) is available as a non-conjugated format. Factor XIII B protein plays a crucial role in blood coagulation, particularly in stabilizing fibrin clots, which is essential for effective hemostasis following tissue injury. Factor XIII B protein is part of the larger Factor XIII complex, consisting of two A subunits and two B subunits; while A subunits are responsible for enzymatic activity that cross-links fibrin, B subunits function as carrier proteins enhancing stability and circulation of the complex in plasma. Understanding Factor XIII B interactions and functions is vital, as deficiencies or dysfunctions can lead to bleeding disorders, highlighting importance in maintaining hemostatic balance. Factor XIII B (GMA-033) antibody is an invaluable tool for researchers studying coagulation pathways and related disorders, providing insights into blood clot formation and stability mechanisms.

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Factor XIII B Antibody (GMA-033) References:

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9. Let's cross-link: diverse functions of the promiscuous cellular transglutaminase factor XIII-A.  |  Mitchell, JL. and Mutch, NJ. 2019. J Thromb Haemost. 17: 19-30. PMID: 30489000
10. Coagulopathy in Type 2 Diabetes Mellitus: Pathological Mechanisms and the Role of Factor XIII-A Single Nucleotide Polymorphisms.  |  Phasha, MN., et al. 2019. Curr Diabetes Rev. 15: 446-455. PMID: 30706822
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12. Factor XIII-A Val34Leu and Tyr204Phe variants influence clot kinetics in a cohort of South African type 2 diabetes mellitus patients.  |  Phasha, MN., et al. 2022. Gene. 834: 146637. PMID: 35671883

The preferred Factor XIII A antibody is Factor XIII A Antibody (A-4): sc-271122.