Molecular structure of Ezetimibe β-D-Glucuronide, CAS Number: 190448-57-8
Ezetimibe β-D-Glucuronide (CAS 190448-57-8)
Alternate Names:
Ezetimibe Phenoxy Glucuronide; Sch 60663; EZM-G
Application:
Ezetimibe β-D-Glucuronide is an antihyperlipoproteinemic
CAS Number:
190448-57-8
Molecular Weight:
585.55
Molecular Formula:
C30H29F2NO9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Ezetimibe β-D-Glucuronide engages with the Niemann-Pick C1-like 1 (NPC1L1) protein to influence cholesterol absorption in the intestines. Scientists use it to examine the glucuronidation process and to understand how glucuronosyltransferase enzymes affect the metabolism of various compounds. It is applied in studies to elucidate the mechanism by which its active form, ezetimibe, operates and to assess the biochemical and physiological impacts of this interaction. Researchers utilize this chemical in analytical chemistry to develop sensitive assays for the detection of metabolites in various matrices, enhancing the ability to track metabolic pathways.
Ezetimibe β-D-Glucuronide (CAS 190448-57-8) References
- Phytoene and Phytofluene Isolated from a Tomato Extract are Readily Incorporated in Mixed Micelles and Absorbed by Caco-2 Cells, as Compared to Lycopene, and SR-BI is Involved in their Cellular Uptake. | Mapelli-Brahm, P., et al. 2018. Mol Nutr Food Res. 62: e1800703. PMID: 30192047
- OATP1B3-1B7 (LST-3TM12) Is a Drug Transporter That Affects Endoplasmic Reticulum Access and the Metabolism of Ezetimibe. | Malagnino, V., et al. 2019. Mol Pharmacol. 96: 128-137. PMID: 31127008
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ezetimibe β-D-Glucuronide, 1 mg | sc-221604 | 1 mg | $372.00 |