EUK 124 (CAS 186299-35-4)
Application:
EUK 124 is a less active analog of EUK 8 and EUK 134
CAS Number:
186299-35-4
Molecular Weight:
476.8
Molecular Formula:
C20H22ClMnN2O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
EUK 124 is a structural analog of EUK 8 and EUK 134 but with significantly reduced activity. EUK 124 and EUK 8 inhibit superoxide-mediated reduction of an electron acceptory.2
EUK 124 (CAS 186299-35-4) References
- Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: structure-activity relationship studies. | Doctrow, SR., et al. 2002. J Med Chem. 45: 4549-58. PMID: 12238934
- Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship? | Van Raamsdonk, JM. and Hekimi, S. 2010. Antioxid Redox Signal. 13: 1911-53. PMID: 20568954
- HOCl-dependent singlet oxygen and hydroxyl radical generation modulate and induce apoptosis of malignant cells. | Bauer, G. 2013. Anticancer Res. 33: 3589-602. PMID: 24023284
- Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: a key role for reactive oxygen species in ischemic brain injury. | Baker, K., et al. 1998. J Pharmacol Exp Ther. 284: 215-21. PMID: 9435181
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EUK 124, 5 mg | sc-205320 | 5 mg | $32.00 | |||
EUK 124, 10 mg | sc-205320A | 10 mg | $61.00 |