Molecular structure of EUK 118, CAS Number: 186299-34-3
EUK 118 (CAS 186299-34-3)
Alternate Names:
(acetato-κO)[[2,2′-[1,2-ethanediylbis[(nitrilo-κN)methylidyne]]bis[3,5-dimethoxyphenolato-κO]](2-)]-manganese
Application:
EUK 118 is a structural analog of EUK 8 and EUK 134
CAS Number:
186299-34-3
Purity:
≥95%
Molecular Weight:
500.4
Molecular Formula:
C22H25MnN2O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
EUK 118 is a structural analog of EUK 8 and EUK 134 with significantly reduced activity and exhibiting a catalase activity of 35 µM O2 formed/minute from 10 mM hydrogen peroxide.2 Superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity) was inhibited by EUK 118 and EUK 8. EUK 118 exhibited no protection of human dermal fibroblasts against hydrogen peroxide-induced cell death.2
EUK 118 (CAS 186299-34-3) References
1 Baker, K., Marcus, C.B., Huffman, K., et al. Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: A key role for reactive oxygen species in ischemic brain injury. J Pharmacol Exp Ther 28Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EUK 118, 5 mg | sc-205319 | 5 mg | $51.00 | |||
EUK 118, 50 mg | sc-205319A | 50 mg | $408.00 |