Molecular structure of Etoposide-d3
Etoposide-d3
See product citations (9)
Application:
Etoposide-d3 is The labeled form of Etoposide
Purity:
98% Isotopic Purity 99%
Molecular Weight:
591.58
Molecular Formula:
C29H29D3O13
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Etoposide-d3 is the labeled form of Etoposide (VP-16) (sc-3512). Etoposide is a topoisomerase II inhibitor that is widely used as an apoptosis inducer. Etoposide exhibits antineoplastic and anti-mitotic properties. Inhibits DNA synthesis and induces double-strand and single-strand DNA breaks. Cell-cycle dependent and cell-cycle specific to late S and G2 phases. Activates p53 resulting in upregulated expression of TRAIL-R2 (DR5) and Bak to overcome TRAIL resistance in Bax-deficient human colon carcinoma cancer cells.
Etoposide-d3 References
- Simultaneous LC-MS/MS bioanalysis of etoposide and paclitaxel in mouse tissues and plasma after oral administration of self-microemulsifying drug-delivery systems. | Li, D., et al. 2018. Biomed Chromatogr. 32: e4192. PMID: 29349799
- Detection of anticancer drugs in wastewater effluents: Grab versus passive sampling. | Cristóvão, MB., et al. 2021. Sci Total Environ. 786: 147477. PMID: 33971591
- Metabolomics analyses of traditional Chinese medicine formula Shuang Huang Lian by UHPLC-QTOF-MS/MS. | Xu, G., et al. 2022. Chin Med. 17: 62. PMID: 35637516
Inhibitor of:
Topo II.Activator of:
p53.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Etoposide-d3, 1 mg | sc-218445 | 1 mg | $449.00 |