Molecular structure of Etoperidone Hydrochloride, CAS Number: 57775-22-1
Etoperidone Hydrochloride (CAS 57775-22-1)
Alternate Names:
2-[3-[4-(3-Chlorophenyl)-1-piperazinyl]propyl]-4,5-diethyl-2,4-dihydro-3H-1,2,4-triazol-3-one hydrochloride
CAS Number:
57775-22-1
Molecular Weight:
414.37
Molecular Formula:
C19H29Cl2N5O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Etoperidone Hydrochloride is a compound that is used in research focused on the study of neurotransmitter systems. In biochemical experiments, it serves as a tool to understand the binding affinity and inhibition kinetics of proteins involved in neurotransmission. The hydrochloride salt form of Etoperidone ensures high solubility in aqueous solutions, which is advantageous for in vitro assays. Research involving Etoperidone Hydrochloride also includes investigations of its interactions with various neurotransmitter receptors and transporters, which can provide insights into the modulation of synaptic activity. Additionally, its influence on cellular signaling pathways is a subject of study, particularly in the context of neurobiology.
Etoperidone Hydrochloride (CAS 57775-22-1) References
- In vitro identification of metabolic pathways and cytochrome P450 enzymes involved in the metabolism of etoperidone. | Yan, Z., et al. 2002. Xenobiotica. 32: 949-62. PMID: 12487725
- Etoperidone, trazodone and MCPP: in vitro and in vivo identification of serotonin 5-HT1A (antagonistic) activity. | Raffa, RB., et al. 1992. Psychopharmacology (Berl). 108: 320-6. PMID: 1387963
- A comparative solid-phase extraction study for the simultaneous determination of fluvoxamine, mianserin, doxepin, citalopram, paroxetine, and etoperidone in whole blood by capillary gas-liquid chromatography with nitrogen-phosphorus detection. | Martínez, MA., et al. 2004. J Anal Toxicol. 28: 174-80. PMID: 15107147
- Effect of etoperidone on the depletion of brain 5-hydroxytryptamine and catecholamines induced respectively by p-chloromethamphetamine and 6-hydroxydopamine in rats. | Carruba, MO., et al. 1979. Pharmacol Res Commun. 11: 169-77. PMID: 155821
- High-performance liquid chromatographic assay with ultraviolet detection for the determination of etoperidone and two active metabolites, 5-(1-hydroxyethyl) etoperidone and 1-(3-chlorophenyl)piperazine, in plasma. | Holland, ML. and Heebner, ET. 1991. J Chromatogr. 567: 433-40. PMID: 1939475
- Blockade of conditioned avoidance responding by trazodone, etoperidone, and MCPP. | Martin, GE., et al. 1989. Psychopharmacology (Berl). 99: 94-7. PMID: 2506609
- Gas chromatographic-mass spectrometric method for trazodone and a deuterated analogue in plasma. | Gammans, RE., et al. 1985. J Chromatogr. 339: 303-12. PMID: 4008570
- The effect of etoperidone, a new potential antidepressant drug, on the central serotonin system. | Przegaliński, E. and Lewandowska, A. 1979. J Neural Transm. 46: 303-12. PMID: 529000
- 1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole. | Fong, MH., et al. 1982. J Pharm Pharmacol. 34: 674-5. PMID: 6128394
- Changed plasma prolactin levels after etoperidone and placebo. | Meco, G., et al. 1984. Int J Clin Pharmacol Res. 4: 117-20. PMID: 6469437
- A comparative pharmacological study of trazodone, etoperidone and 1-(m-chlorophenyl)piperazine. | Cioli, V., et al. 1984. Pharmacol Res Commun. 16: 85-100. PMID: 6701182
- Acute cardiovascular toxicity of trazodone, etoperidone and imipramine in rats. | Lisciani, R., et al. 1978. Toxicology. 10: 151-8. PMID: 684760
- Preliminary study of the biotransformation of two new drugs, trazodone and etoperidone. | Melzacka, M., et al. 1980. Pol J Pharmacol Pharm. 32: 551-6. PMID: 7255270
- Identification of four plasma metabolites of Etoperidone in dogs. | Wu, WN., et al. 1995. J Pharm Biomed Anal. 13: 177-84. PMID: 7766726
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Etoperidone Hydrochloride, 5 mg | sc-211494 | 5 mg | $291.00 | |||
Etoperidone Hydrochloride, 250 mg | sc-211494A | 250 mg | $510.00 |