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ETO-2 Antibody (G-7) is a mouse monoclonal IgM antibody that detects ETO-2 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ETO-2, also known as MTG16, is a crucial member of the ETO transcription factor family, which plays a significant role in regulating gene expression and cellular differentiation. ETO-2 is primarily located in the nucleus, where ETO-2 interacts with various DNA-binding proteins and transcriptional regulators, including the nuclear receptor corepressor (N-CoR). Nuclear localization of ETO-2 is vital for function, as this positioning allows for precise modulation of transcriptional activity in response to cellular signals. ETO-2′s ability to form complexes with other transcription factors is essential for maintaining proper gene expression patterns, which are critical for normal cellular processes and development. Dysregulation of ETO-2 and associated pathways can lead to various hematological malignancies, underscoring the importance of studying ETO-2 in cancer research. Anti-ETO-2 antibody (G-7) provides a reliable tool for researchers investigating the role of ETO-2 in transcriptional regulation and disease implications.
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Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ETO-2 Antibody (G-7) | sc-390332 | 200 µg/ml | $316.00 | |||
ETO-2 (G-7) Neutralizing Peptide | sc-390332 P | 100 µg/0.5 ml | $68.00 | |||
ETO-2 Antibody (G-7) X | sc-390332 X | 200 µg/0.1 ml | $316.00 |