Date published: 2026-5-26

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Etiroxate (CAS 17365-01-4)

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Alternate Names:
O-(4-Hydroxy-3,5-diiodo-phenyl)-3,5-diiodo-α-methyl-DL-tyrosine Ethyl Ester; DL-α-Methyl-thyroxine Ethyl Ester; CG-635
Application:
Etiroxate is an antilipaemic derivative of thyroxine
CAS Number:
17365-01-4
Molecular Weight:
818.95
Molecular Formula:
C18H17I4NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Etiroxate is an antilipemic derivative of thyroxine.


Etiroxate (CAS 17365-01-4) References

  1. Discrimination and molecular design of new theoretical hypolipaemic agents using the molecular connectivity functions.  |  Cercos-del-Pozo, RA., et al. 2000. J Chem Inf Comput Sci. 40: 178-84. PMID: 10661565
  2. Fragmentation of toxicologically relevant drugs in negative-ion liquid chromatography-tandem mass spectrometry.  |  Niessen, WM. 2012. Mass Spectrom Rev. 31: 626-65. PMID: 22829116
  3. Pharmacophore Model Refinement for 11β-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations.  |  Vuorinen, A., et al. 2014. Mol Inform. 33: 15-25. PMID: 27485195
  4. The forgotten effects of thyrotropin-releasing hormone: Metabolic functions and medical applications.  |  Fröhlich, E. and Wahl, R. 2019. Front Neuroendocrinol. 52: 29-43. PMID: 29935915
  5. [The effect of repeated administration of triiodothyronine or etiroxate on liver regeneration in rats after partial hepatectomy].  |  Cervinková, Z., et al. 1985. Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove Suppl. 28: 291-8. PMID: 3879914
  6. [Therapy of hyperlipoproteinemia type IIa and IIb with etiroxate-HCl. Dose-response comparison].  |  Banz, H. and Gall, FP. 1979. Fortschr Med. 97: 1942-1947. PMID: 520990
  7. Effect of etiroxate on LCAT activity and on certain energy metabolism enzymes in the rat.  |  Dobiásová, M., et al. 1982. Physiol Bohemoslov. 31: 323-7. PMID: 6215662
  8. Effect of triiodothyronine or etiroxate on DNA synthesis in intact and regenerating liver.  |  Cervinková, Z., et al. 1984. Physiol Bohemoslov. 33: 501-6. PMID: 6241723
  9. Rate of LCAT-mediated cholesterol esterification and serum lipids during etiroxate therapy in hyperlipoproteinemia.  |  Dobiásová, M., et al. 1982. Atherosclerosis. 42: 251-61. PMID: 7073804
  10. New Hypolipaemic Agents Designed by Molecular Topology: Pharmacological Studies of 2, 6‐Di‐tert‐butyl‐4‐methylpyridine and 2, 6‐Di‐tert‐butylpyridine  |  Cercós‐del‐Pozo, R. A., Pérez‐Giménez, F., Salabert‐Salvador, M. T., García‐March, F. J., & Murcia‐Soler, M. 1999. Quantitative Structure‐Activity Relationships. 18(5): 464-473.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Etiroxate, 10 mg

sc-218440
10 mg
$300.00