Molecular structure of Ethyl vinyl sulfone, CAS Number: 1889-59-4
Ethyl vinyl sulfone (CAS 1889-59-4)
See product citations (1)
Alternate Names:
(ethanesulfonyl)ethene
CAS Number:
1889-59-4
Molecular Weight:
120.17
Molecular Formula:
C4H8O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Ethyl vinyl sulfone (EVS) stands as an organosulfur compound renowned for its exceptional properties, rendering it highly valuable across numerous applications. This colorless, odorless, and non-toxic liquid exhibits solubility in water and alcohols, while remaining insoluble in ether, ketone, and hydrocarbons. Ethyl vinyl sulfone has found extensive utility as a reagent in diverse chemical syntheses, as a solvent for various organic compounds, and as a plasticizer for polymers.It engages in interactions with an array of proteins and enzymes. Moreover, it has demonstrated interactions with proteins involved in cell proliferation and apoptosis regulation.
Ethyl vinyl sulfone (CAS 1889-59-4) References
- A novel one-pot reaction: zwitterionic rhodium complex-catalyzed hydroaminovinylation of vinyl sulfones and a vinylphosphonate. | Lin, YS., et al. 2001. J Am Chem Soc. 123: 7719-20. PMID: 11481003
- Development of peptidomimetics with a vinyl sulfone warhead as irreversible falcipain-2 inhibitors. | Ettari, R., et al. 2008. J Med Chem. 51: 988-96. PMID: 18232656
- Sortase inhibitor phenyl vinyl sulfone inhibits Renibacterium salmoninarum adherence and invasion of host cells. | Sudheesh, PS., et al. 2007. Dis Aquat Organ. 78: 115-27. PMID: 18286808
- Development of novel peptidomimetics containing a vinyl sulfone moiety as proteasome inhibitors. | Ettari, R., et al. 2011. ChemMedChem. 6: 1228-37. PMID: 21506279
- Enhanced toxicity of the protein cross-linkers divinyl sulfone and diethyl acetylenedicarboxylate in comparison to related monofunctional electrophiles. | West, JD., et al. 2011. Chem Res Toxicol. 24: 1457-9. PMID: 21812477
- One-step 'click' method for generating vinyl sulfone groups on hydroxyl-containing water-soluble polymers. | Yu, Y. and Chau, Y. 2012. Biomacromolecules. 13: 937-42. PMID: 22229738
- Oxidative coupling of Michael acceptors with aryl nucleophiles produced through rhodium-catalyzed C-C bond activation. | Gregerson, CE., et al. 2017. Org Biomol Chem. 15: 5944-5948. PMID: 28675229
- Investigation and Demonstration of Catalyst/Initiator-Driven Selectivity in Thiol-Michael Reactions. | Frayne, SH., et al. 2017. J Org Chem. 82: 7946-7956. PMID: 28695735
- Target identification reveals protein arginine methyltransferase 1 is a potential target of phenyl vinyl sulfone and its derivatives. | Yu, CH., et al. 2018. Biosci Rep. 38: PMID: 29540535
- Bi-affinity Electrolyte Optimizing High-Voltage Lithium-Rich Manganese Oxide Battery via Interface Modulation Strategy. | Yuan, X., et al. 2023. Angew Chem Int Ed Engl. e202304121. PMID: 37226711
- The Reactivity of Hydroxyl Groups at Different Tactic Sequences on Poly(vinyl alcohol) in the Addition Reaction with Vinyl Sulfoxides and Vinyl Sulfones | , et al. 1991. Polymer JournalI. 23: 1105–1109.
- Relative reactivity and selectivity of vinyl sulfones and acrylates towards the thiol–Michael addition reaction and polymerization | Chatani, S., Nair, D. P., & Bowman, C. N. 2013. Polymer Chemistry. 4(4): 1048-1055.
- Mechanistic Modeling of the Thiol–Michael Addition Polymerization Kinetics: Structural Effects of the Thiol and Vinyl Monomers | Sijia Huang, Jasmine Sinha, Maciej Podgórski, Xinpeng Zhang, Mauro Claudino, and Christopher N. Bowman*. 2018. Macromolecules. 51(15): 5979–5988.
Inhibitor of:
cathepsin A.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ethyl vinyl sulfone, 5 g | sc-228082 | 5 g | $104.00 |