Molecular structure of Ethyl pyruvate, CAS Number: 617-35-6
Ethyl pyruvate (CAS 617-35-6)
See product citations (2)
Alternate Names:
Pyruvic Acid Ethyl Ester; Ethyl 2-Oxopropanoate
Application:
Ethyl pyruvate is an organic building block that is a novel anti inflammatory in vitro
CAS Number:
617-35-6
Purity:
≥98%
Molecular Weight:
116.12
Molecular Formula:
C5H8O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ethyl pyruvate (EP), also known as ethyl 2-oxopropanoate, is a naturally occurring organic compound present in various foods, including fruits and vegetables. It serves as a intermediate in the metabolic processes of carbohydrates, lipids, and proteins. Additionally, It is a novel anti inflammatory in vitro. Ethyl pyruvate′s mechanism of action is not yet completely elucidated, but it is believed to engage in multiple pathways. One proposed mechanism suggests its involvement as a free radical scavenger, effectively reducing oxidative stress and mitigating inflammation.
Ethyl pyruvate (CAS 617-35-6) References
- Ethyl pyruvate alleviates early brain injury following subarachnoid hemorrhage in rats. | Fang, R., et al. 2016. Acta Neurochir (Wien). 158: 1069-76. PMID: 27072679
- Ethyl pyruvate ameliorates inflammatory arthritis in mice. | Jung, SM., et al. 2017. Int Immunopharmacol. 52: 333-341. PMID: 28987932
- Ethyl Pyruvate Induces Tolerogenic Dendritic Cells. | Djedovic, N., et al. 2019. Front Immunol. 10: 157. PMID: 30792716
- Ethyl pyruvate confers protection against endotoxemia and sepsis by inhibiting caspase-11-dependent cell pyroptosis. | Qiu, X., et al. 2020. Int Immunopharmacol. 78: 106016. PMID: 31796383
- Ethyl pyruvate protects against sepsis-associated encephalopathy through inhibiting the NLRP3 inflammasome. | Zhong, X., et al. 2020. Mol Med. 26: 55. PMID: 32517686
- Ethyl Pyruvate Promotes Proliferation of Regulatory T Cells by Increasing Glycolysis. | Koprivica, I., et al. 2020. Molecules. 25: PMID: 32916780
- Ethyl Pyruvate-Derived Transdifferentiation of Astrocytes to Oligodendrogenesis in Cuprizone-Induced Demyelinating Model. | He, Y., et al. 2021. Neurotherapeutics. 18: 488-502. PMID: 33140235
- Ethyl pyruvate improves white matter remodeling in rats after traumatic brain injury. | Mao, L., et al. 2021. CNS Neurosci Ther. 27: 113-122. PMID: 33369165
- Ethyl pyruvate supplemented in drinking water ameliorates experimental nonalcoholic steatohepatitis. | Sun, X., et al. 2021. Biomed Pharmacother. 137: 111392. PMID: 33761609
- Ethyl Pyruvate Attenuates Microglial NLRP3 Inflammasome Activation via Inhibition of HMGB1/NF-κB/miR-223 Signaling. | Olcum, M., et al. 2021. Antioxidants (Basel). 10: PMID: 34066647
- Ethyl Pyruvate Ameliorates Experimental Autoimmune Myocarditis. | Gajić, D., et al. 2021. Biomolecules. 11: PMID: 34944410
- Ethyl pyruvate attenuates isoproterenol-induced myocardial infarction in rats: Insight to TNF-α-mediated apoptotic and necroptotic signaling interplay. | Al-Botaty, BM., et al. 2022. Int Immunopharmacol. 103: 108495. PMID: 34973531
- Protective effect of ethyl pyruvate on amikacin-induced ototoxicity in rats. | Dedeoğlu, S. and Ayral, M. 2022. Eur Rev Med Pharmacol Sci. 26: 2460-2466. PMID: 35442461
- Ethyl Pyruvate Alleviating Inflammatory Response after Diabetic Cerebral Hemorrhage. | Wang, Y., et al. 2022. Curr Neurovasc Res. 19: 196-202. PMID: 35657042
- Ethyl pyruvate protects SHSY5Y cells against 6-hydroxydopamine-induced neurotoxicity by upregulating autophagy. | Luo, Y. and Sakamoto, K. 2023. PLoS One. 18: e0281957. PMID: 36795720
Inhibitor of:
HMG-1, LIAS, S-100 α chain, and SCARF (scavenger receptor class F).Activator of:
LDH-B.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ethyl pyruvate, 25 g | sc-257508 | 25 g | $32.00 |