Date published: 2025-10-14

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Ethyl isothiocyanate (CAS 542-85-8)

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CAS Number:
542-85-8
Molecular Weight:
87.14
Molecular Formula:
C2H5NCS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl isothiocyanate (EIT) is a naturally occurring chemical compound that can be found in various plants. Due to its unique characteristics, Ethyl isothiocyanate has found extensive applications in the realm of scientific research, spanning synthesis, biochemistry, and physiology. Ethyl isothiocyanate finds broad utility in scientific research across multiple domains. In organic synthesis, it serves as a highly reactive nucleophile, facilitating the synthesis of diverse compounds. In the field of biochemistry, Ethyl isothiocyanate is employed to investigate enzyme kinetics and protein-ligand interactions.


Ethyl isothiocyanate (CAS 542-85-8) References

  1. Diphosphanylketenimines: new reagents for the synthesis of unique phosphorus heterocycles.  |  Ruiz, J., et al. 2002. Chemistry. 8: 3872-8. PMID: 12360928
  2. Versatile stereoselective cycloadditions between heterocumulenes and phosphagermaallene Tip(tBu)Ge=C=PMes*: experimental and theoretical investigations.  |  Ghereg, D., et al. 2011. Chemistry. 17: 12763-72. PMID: 21956731
  3. Differential hepatic GSTA2 expression of arylalkyl isothiocyanates in vivo and in vitro: the molecular mechanism of gene induction by phenethyl isothiocyanate.  |  Gum, SI. and Cho, MK. 2013. Mol Nutr Food Res. 57: 2223-32. PMID: 24039128
  4. Investigation of diethylthiourea and ethyl isothiocyanate as potent skin allergens in chloroprene rubber.  |  Ramzy, AG., et al. 2015. Contact Dermatitis. 72: 139-46. PMID: 25532938
  5. Peptide Reactivity of Isothiocyanates--Implications for Skin Allergy.  |  Karlsson, I., et al. 2016. Sci Rep. 6: 21203. PMID: 26883070
  6. Isothiocyanates are important as haptens in contact allergy to chloroprene rubber.  |  Ramzy, AG., et al. 2017. Br J Dermatol. 177: 522-530. PMID: 28295200
  7. Discovery of New Apoptosis-Inducing Agents for Breast Cancer Based on Ethyl 2-Amino-4,5,6,7-Tetra Hydrobenzo[b]Thiophene-3-Carboxylate: Synthesis, In Vitro, and In Vivo Activity Evaluation.  |  Gad, EM., et al. 2020. Molecules. 25: PMID: 32481682
  8. [ALLERGIC CONTACT DERMATITIS DUE TO NITRILE RUBBER GLOVES: ETHYL ISOTHIOCYANATE AND BUTYL ISOTHIOCYANATE AS POSSIBLE CAUSATIVE CHEMICALS].  |  Iijima, S., et al. 2020. Arerugi. 69: 669-677. PMID: 32963190
  9. Reversible Cycling of Graphite Electrodes in Propylene Carbonate Electrolytes Enabled by Ethyl Isothiocyanate.  |  Li, X., et al. 2021. ACS Appl Mater Interfaces. 13: 26023-26033. PMID: 34032410

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl isothiocyanate, 10 g

sc-239935
10 g
$60.00