Date published: 2025-12-18

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Ethyl DL-Leucate (CAS 10348-47-7)

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Alternate Names:
DL-Leucic Acid Ethyl Ester; Ethyl DL-2-Hydroxy-4-methylvalerate; DL-2-Hydroxy-4-methylvaleric Acid Ethyl Ester
CAS Number:
10348-47-7
Molecular Weight:
160.21
Molecular Formula:
C8H16O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl DL-Leucate, with the CAS number 10348-47-7, is the ethyl ester derivative of DL-leucine, an amino acid that exists as a racemic mixture of its L- and D-isomers. This chemical structure features the characteristic carboxyl group of amino acids esterified with ethanol, which modifies its solubility and reactivity compared to its parent amino acid, leucine. In research, Ethyl DL-Leucate is predominantly used as a reagent in synthetic chemistry, particularly in the synthesis of peptides and other ester-linked compounds. Its utility arises from the ester group, which can be targeted in reactions such as hydrolysis and transesterification, allowing for the introduction of other functional groups or for incorporation into larger, more complex molecules. Furthermore, the presence of both L- and D-isomers in the racemic mixture provides a unique opportunity to study stereochemical effects in synthetic pathways and reaction mechanisms. In fields like organic chemistry, Ethyl DL-Leucate serves as a versatile building block for the synthesis of various organic compounds. It is also used in studies focusing on the stabilization of proteins and enzymes, where understanding the interaction between esterified amino acids and protein structures can explain mechanisms relevant to the stability and function of biocatalysts. Additionally, this compound aids in the exploration of new methods for peptide bond formation, an essential process in the production of peptides and proteins in laboratory settings.


Ethyl DL-Leucate (CAS 10348-47-7) References

  1. Distribution and organoleptic impact of ethyl 2-hydroxy-4-methylpentanoate enantiomers in wine.  |  Lytra, G., et al. 2012. J Agric Food Chem. 60: 1503-9. PMID: 22224424
  2. Aldehyde Accumulation in Aged Alcoholic Beer: Addressing Acetaldehyde Impacts on Upper Aerodigestive Tract Cancer Risks.  |  Moreira, MTG., et al. 2022. Int J Mol Sci. 23: PMID: 36430619
  3. Comparison of Aroma Compounds and Sensory Characteristics between Two Different Types of Rice-Based Baijiu.  |  Wu, F., et al. 2024. Foods. 13: PMID: 38472793

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl DL-Leucate, 5 g

sc-294549
5 g
$86.00

Ethyl DL-Leucate, 25 g

sc-294549A
25 g
$251.00