Ethyl-D-erythro-sphingosinate Hydrochloride (CAS 355803-79-1)

Ethyl-D-erythro-sphingosinate Hydrochloride, catalogued under CAS number 355803-79-1, is a synthetic analog of naturally occurring sphingosine, a crucial component in the lipid metabolism of cellular membranes. This particular compound is modified by the addition of an ethyl group at the terminal hydroxyl position, transforming it into a more lipophilic ester and enhancing its solubility in organic solvents, which is advantageous for various biochemical applications. The ′D-erythro′ designation refers to the specific stereochemistry of the molecule, crucial for its interaction with biological molecules and its integration into lipid assemblies. The inclusion of a hydrochloride group improves the compound′s stability and makes it easier to handle in aqueous solutions. In research, Ethyl-D-erythro-sphingosinate Hydrochloride is predominantly used to study the role and behavior of sphingosine in synthetic systems, providing insights into the structure and function of sphingolipids in membranes. It serves as a vital tool in the exploration of lipid rafts and the signaling pathways associated with sphingolipid metabolism. Furthermore, the altered physical properties due to the ethyl ester group allow researchers to investigate the effects of modifications on lipid-lipid and lipid-protein interactions within membranes, contributing to a broader understanding of membrane dynamics and lipidomics.