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Ethyl Biscoumacetate (CAS 548-00-5)

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Alternate Names:
Bis(4-hydroxy-2-oxo-2H-1-benzopyran-3-yl)acetic Acid Ethyl Ester; Pelentan; Tromexan
Application:
Ethyl Biscoumacetate is a coumarin used as an anticoagulant
CAS Number:
548-00-5
Molecular Weight:
408.36
Molecular Formula:
C22H16O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl biscoumacetate is a chemical compound primarily used in organic synthesis and materials science. It is structurally related to coumarins, which are known for their diverse applications and biological activities. In the realm of organic chemistry, ethyl biscoumacetate is often used as a precursor or intermediate in the synthesis of more complex molecules, including polymers and potential catalysts. Researchers also investigate its role in the creation of novel organic compounds, particularly those that might exhibit unique optical properties due to the conjugated system present in the coumarin moiety. In materials science, its properties are explored for the development of organic light-emitting diodes (OLEDs) and other electronic devices, where its ability to transport electrons can be advantageous. Furthermore, the compound′s potential in the fabrication of sensors and other responsive materials is another avenue of research, as the coumarin derivatives are known to interact with various stimuli, leading to measurable changes in their properties.


Ethyl Biscoumacetate (CAS 548-00-5) References

  1. The physiological disposition of ethyl biscoumacetate (tromexan) in man and a method for its estimation in biological material.  |  BRODIE, BB., et al. 1952. J Pharmacol Exp Ther. 106: 453-63. PMID: 13023556
  2. Antagonistic effect of A.C.T.H. and cortisone on the anticoagulant activity of ethyl biscoumacetate.  |  CHATTERJEA, JB. and SALOMON, L. 1954. Br Med J. 2: 790-2. PMID: 13199310
  3. Control of ethyl biscoumacetate (tromexan) therapy by standardized clotting time of whole blood.  |  MAYER, GA. and CONNELL, WF. 1957. Can Med Assoc J. 77: 930-8. PMID: 13479846
  4. Effect of warfarin, ethyl biscoumacetate, and phenindione on the factors of the prothrombin complex.  |  NOREN, I. and QUICK, AJ. 1963. J Lab Clin Med. 61: 302-7. PMID: 13938922
  5. The effects of menadione, ethyl biscoumacetate, and sodium salicylate on the metabolism of mucopolysaccharides in the aortic wall and liver of rats.  |  Sharaev, PN., et al. 1977. Cor Vasa. 19: 151-5. PMID: 143357
  6. Clinical experiences with the anticoagulant, ethyl biscoumacetate (N.N.R.).  |  BARKER, NW., et al. 1951. Proc Staff Meet Mayo Clin. 26: 162-7. PMID: 14827945
  7. Bishydroxycoumarin, ethyl biscoumacetate, and 4-hydroxycoumarin anticoagulant No. 63; comparative effects.  |  BARKER, NW., et al. 1952. J Am Med Assoc. 148: 274-7. PMID: 14888460
  8. Determination of ethyl biscoumacetate and its metabolite 7-hydroxyethyl biscoumacetate in human serum by high-performance liquid chromatography and mass spectrometry.  |  Pospísil, J., et al. 1992. J Chromatogr. 574: 71-5. PMID: 1629290
  9. Effect of ethyl biscoumacetate on the incorporation of precursors into nuclear and mitochondrial DNA of cells grown in culture.  |  Georgatsos, JG. and Karemfyllis, T. 1970. Arch Biochem Biophys. 141: 387-8. PMID: 4320356
  10. Methylphenidate interaction with both anticonvulsants and ethyl biscoumacetate.  |  Garrettson, LK., et al. 1969. JAMA. 207: 2053-6. PMID: 5818377
  11. The effect of some sedatives (phenobarbital, gluthetimide, chlordiazepoxide, chloral hydrate) on the rate of disappearance of ethyl biscoumacetate from the plasma.  |  van Dam, FE. and Gribnau-Overkamp, MJ. 1967. Folia Med Neerl. 10: 141-5. PMID: 6073948
  12. High-performance liquid chromatographic determination of ethyl biscoumacetate in human plasma.  |  Arman, M. and Jamali, F. 1983. J Chromatogr. 272: 406-10. PMID: 6833438
  13. Pharmacokinetics of ethyl biscoumacetate and its metabolite 7-hydroxy ethyl biscoumacetate in healthy volunteers.  |  Perlík, F. and Patzelová, V. 1994. Int J Clin Pharmacol Ther. 32: 622-4. PMID: 7874379

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl Biscoumacetate, 100 mg

sc-394088
100 mg
$284.00