Date published: 2026-2-8

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Ethyl α-chlorophenylacetate (CAS 4773-33-5)

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Alternate Names:
Ethyl 1-chlorophenylacetate
CAS Number:
4773-33-5
Purity:
≥96%
Molecular Weight:
198.65
Molecular Formula:
C10H11ClO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl α-chlorophenylacetate is a chemical compound that functions as an intermediate in the synthesis of various organic compounds. It acts as an acylating agent in organic reactions, facilitating the formation of esters and other derivatives. The compound′s mode of action involves its ability to undergo nucleophilic acylation, where the α-chlorophenyl group serves as an electrophile, reacting with nucleophiles to form new carbon-carbon or carbon-heteroatom bonds. Role in organic synthesis is significant, as it enables the creation of diverse molecular structures through acylation reactions. Its mode of action at the molecular level involves the transfer of the α-chlorophenylacetyl group to nucleophilic substrates, leading to the formation of esters and related compounds. Function in organic synthesis is for the development of various chemical products and materials.


Ethyl α-chlorophenylacetate (CAS 4773-33-5) References

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  2. Straightforward synthesis of dihydrobenzofurans and benzofurans from arynes.  |  Yoshioka, E., et al. 2013. Org Lett. 15: 3938-41. PMID: 23859157
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  4. Poly(vinylidene fluoride-co-chlorotrifluoroethylene) Modification via Organocatalyzed Atom Transfer Radical Polymerization.  |  Hu, X., et al. 2017. Macromol Rapid Commun. 38: PMID: 28921703
  5. Photoinduced Organocatalyzed Atom Transfer Radical Polymerization (O-ATRP): Precision Polymer Synthesis Using Organic Photoredox Catalysis.  |  Corbin, DA. and Miyake, GM. 2022. Chem Rev. 122: 1830-1874. PMID: 34842426
  6. Rational Design of Photocatalysts for Controlled Polymerization: Effect of Structures on Photocatalytic Activities.  |  Wu, C., et al. 2022. Chem Rev. 122: 5476-5518. PMID: 34982536
  7. A cross-sectional study to find association of VDR gene polymorphism with non-syndromic congenital ichthyosis and with vitamin D deficiency.  |  Kaushik, H., et al. 2023. Arch Dermatol Res. 315: 551-557. PMID: 36192561

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl α-chlorophenylacetate, 5 g

sc-235029
5 g
$49.00