Date published: 2026-5-30

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Ethyl 6-bromopicolinate (CAS 21190-88-5)

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CAS Number:
21190-88-5
Molecular Weight:
230.06
Molecular Formula:
C8H8BrNO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl 6-bromopicolinate, also referred to as EBP-2C, is an organic compound characterized by a pyridine ring bearing a bromine atom. This colorless solid is soluble in water and has garnered significant attention in diverse scientific research endeavors. Its distinctive structure facilitates interactions with an array of biological molecules, rendering it an appealing subject of investigation. As a reagent, it has contributed to the synthesis of novel compounds, including small-molecule inhibitors that target protein-protein interactions. Moreover, it has served as a valuable model compound for exploring the intricate relationships between structure and activity in biological molecules like enzymes and receptors. While the precise mechanism of action of Ethyl 6-bromopicolinate remains elusive, it is known to engage with a variety of biological molecules, such as proteins and enzymes. The highly reactive bromine atom attached to the pyridine ring likely accounts for its interaction capabilities, as it readily forms covalent bonds with these molecules.


Ethyl 6-bromopicolinate (CAS 21190-88-5) References

  1. Synthesis and evaluation of tetrahydroisoquinoline-benzimidazole hybrids as multifunctional agents for the treatment of Alzheimer's disease.  |  Fang, Y., et al. 2019. Eur J Med Chem. 167: 133-145. PMID: 30771601
  2. Insights on JAK2 Modulation by Potent, Selective, and Cell-Permeable Pseudokinase-Domain Ligands.  |  Liosi, ME., et al. 2022. J Med Chem. 65: 8380-8400. PMID: 35653642

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl 6-bromopicolinate, 1 g

sc-279139
1 g
$93.00

Ethyl 6-bromopicolinate, 5 g

sc-279139A
5 g
$323.00