Ethyl 4,4,4-trifluoroacetoacetate (CAS 372-31-6)
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Ethyl 4,4,4-trifluoroacetoacetate is an organofluorine compound employed in various research applications, especially in the field of synthetic organic chemistry. Its utility lies in its ability to introduce a trifluoromethyl group into a wide array of organic molecules, a moiety of interest for its electronic and steric effects. Researchers utilize ethyl 4,4,4-trifluoroacetoacetate in the synthesis of heterocyclic compounds, exploring its reactivity in condensation reactions with amines, hydrazines, and other nucleophiles. The compound is also a key starting material in the preparation of fluorinated analogs of bioactive molecules, enhancing the understanding of how fluorine incorporation affects biological activity. In addition, it serves as a precursor for the generation of enolates that participate in various carbon-carbon bond-forming reactions, an aspect for the construction of complex molecular architectures in the realm of organic synthesis.
Ethyl 4,4,4-trifluoroacetoacetate (CAS 372-31-6) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ethyl 4,4,4-trifluoroacetoacetate, 5 g | sc-239914 | 5 g | $30.00 | |||
Ethyl 4,4,4-trifluoroacetoacetate, 25 g | sc-239914A | 25 g | $113.00 |