Date published: 2026-2-2

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Ethyl 2-nitropropionate (CAS 2531-80-8)

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Alternate Names:
2-Nitropropionic acid ethyl ester
Application:
Ethyl 2-nitropropionate is a nitro ester for use in enantioselective Michael reactions
CAS Number:
2531-80-8
Molecular Weight:
147.13
Molecular Formula:
C5H9NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl 2-nitropropionate is in organic synthesis, focusing on the study of nitro compounds and their applications in building complex molecular structures. Ethyl 2-nitropropionate is particularly for its role in the synthesis of gamma-amino acids and their derivatives, which are important in developing novel organic molecules. They explore the reactivity of Ethyl 2-nitropropionate under various conditions to optimize reaction pathways and improve the efficiency of synthesis processes. It is also utilized in studies related to the Michael addition reaction, where it acts as a nucleophile. Ethyl 2-nitropropionate is investigated for its potential use in polymer chemistry, where its incorporation into polymers could lead to materials with unique properties such as enhanced durability or reactivity.


Ethyl 2-nitropropionate (CAS 2531-80-8) References

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  6. Highly enantioselective organocatalytic Michael addition of nitroalkanes to 4-oxo-enoates.  |  Lu, HH., et al. 2009. Chem Commun (Camb). 4251-3. PMID: 19585037
  7. Synthesis and characterization of several carbamoyl- and methylcarbamoyl-substituted EMPO derivatives.  |  Stolze, K., et al. 2009. Bioorg Med Chem. 17: 7572-84. PMID: 19800243
  8. Comparison of Volatile Compounds from Chungkuk-Jang and Itohiki-Natto.  |  Tanaka, T., et al. 1998. Biosci Biotechnol Biochem. 62: 1440-4. PMID: 27397006
  9. Palladium-catalyzed synthesis of monofluoroalkenes from 3,3-difluoropropenes using dimethylmalonate and derivatives as nucleophiles.  |  Drouin, M., et al. 2017. Org Biomol Chem. 15: 2376-2384. PMID: 28244537
  10. A Persulfide Donor Responsive to Reactive Oxygen Species: Insights into Reactivity and Therapeutic Potential.  |  Powell, CR., et al. 2018. Angew Chem Int Ed Engl. 57: 6324-6328. PMID: 29697170
  11. Nitro-treatment of composted poultry litter; effects on Salmonella, E. coli and nitrogen metabolism.  |  Ruiz-Barrera, O., et al. 2020. Bioresour Technol. 310: 123459. PMID: 32389429
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  13. Inhibitory Effect of Select Nitrocompounds and Chlorate against Yersinia ruckeri and Yersinia aleksiciae In Vitro.  |  Latham, EA., et al. 2022. Pathogens. 11: PMID: 36422632

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl 2-nitropropionate, 1 g

sc-234941
1 g
$36.00