Ethyl 2-chloro-4,4,4-trifluoroacetoacetate (CAS 363-58-6)

Ethyl 2-chloro-4,4,4-trifluoroacetoacetate (ETCA) is a versatile organofluorine compound extensively utilized in scientific research as a reagent for organic synthesis. It is known by various names such as ethyl chloroformate, ethyl trifluoroacetoacetate, or 2-chloro-1,1,1-trifluoroethanoyl chloride. Ethyl 2-chloro-4,4,4-trifluoroacetoacetate holds great significance in the realm of organic synthesis as it enables the production of a diverse range of compounds. It serves as a valuable reagent for synthesizing fluorinated compounds. In scientific research, Ethyl 2-chloro-4,4,4-trifluoroacetoacetate finds extensive applications as a reagent in organic synthesis, facilitating the creation of various compounds. It also acts as a catalyst in the synthesis of fluorinated compounds. As an organofluorine compound, Ethyl 2-chloro-4,4,4-trifluoroacetoacetate′s mechanism of action hinges on its ability to interact with specific functional groups present in organic molecules. It acts as a nucleophilic reagent, engaging with nucleophilic functional groups like alcohols, amines, and thiols. These reactions lead to the formation of highly stable carbon-fluorine bonds, which are resistant to hydrolysis.