Date published: 2026-1-20

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Ethyl 2,3-epoxypropanoate (CAS 4660-80-4)

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Alternate Names:
Glycidic acid ethyl ester; Ethyl oxirane-2-carboxylate
CAS Number:
4660-80-4
Molecular Weight:
116.12
Molecular Formula:
C5H8O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ethyl 2,3-epoxypropanoate is a versatile compound involved in a range of scientific research applications. This cyclic ester of oxirane is a colorless liquid. Its solubility is limited in water but is more pronounced in substances like alcohol, ether, and acetone. The compound′s broad use in scientific research includes functioning as a reagent for organic synthesis and serving as a catalyst for the polymerization of styrene among other monomers. It′s also employed in the creation of substances such as food additives and fragrances. Ethyl oxirane-2-carboxylate contributes to the production of polymers, like polyethylene and polypropylene, and aids in the synthesis of biodegradable plastics. The exact mechanism through which ethyl oxirane-2-carboxylate operates remains unclear. However, it′s known to serve as a catalyst in the polymerization of styrene and other monomers, with the oxirane ring-opening reaction considered a primary action mechanism in this procedure.


Ethyl 2,3-epoxypropanoate (CAS 4660-80-4) References

  1. Structure-activity relationships in toll-like receptor-2 agonistic diacylthioglycerol lipopeptides.  |  Wu, W., et al. 2010. J Med Chem. 53: 3198-213. PMID: 20302301
  2. Pathways to Identify Electrophiles In Vivo Using Hemoglobin Adducts: Hydroxypropanoic Acid Valine Adduct and Its Possible Precursors.  |  Vryonidis, E., et al. 2022. Chem Res Toxicol. 35: 2227-2240. PMID: 36395356

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethyl 2,3-epoxypropanoate, 1 g

sc-234952
1 g
$136.00