Date published: 2026-4-30

1-800-457-3801

SCBT Portrait Logo
Seach Input

Ethoxyquin Dimer (CAS 74681-77-9)

5.0(1)
Write a reviewAsk a question

Alternate Names:
1,8′-Di(1,2-dihydro-6-ethoxy-2,2,4-trimethylquinoline); EQDM
Application:
Ethoxyquin Dimer is a major oxidative metabolite of the antidegradant Ethoxyquin
CAS Number:
74681-77-9
Molecular Weight:
432.60
Molecular Formula:
C28H36N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Ethoxyquin Dimer is the major oxidative metabolite of the antidegradant Ethoxyquin that is naturally observed in the muscle of Atlantic salmon. It has been used in a variety of scientific research applications, including as an antioxidant, a preservative, and a biocide. It has also been used in the production of pharmaceuticals, cosmetics, and food products.


Ethoxyquin Dimer (CAS 74681-77-9) References

  1. Hepatic metabolism, phase I and II biotransformation enzymes in Atlantic salmon (Salmo Salar, L) during a 12 week feeding period with graded levels of the synthetic antioxidant, ethoxyquin.  |  Berdikova Bohne, VJ., et al. 2007. Food Chem Toxicol. 45: 733-46. PMID: 17150295
  2. Simultaneous quantitative determination of the synthetic antioxidant ethoxyquin and its major metabolite in Atlantic salmon (Salmo salar, L), ethoxyquin dimer, by reversed-phase high-performance liquid chromatography with fluorescence detection.  |  Bohne, VJ., et al. 2007. J AOAC Int. 90: 587-97. PMID: 17474529
  3. Accumulation and depuration of the synthetic antioxidant ethoxyquin in the muscle of Atlantic salmon (Salmo salar L.).  |  Bohne, VJ., et al. 2008. Food Chem Toxicol. 46: 1834-43. PMID: 18329775
  4. Levels of synthetic antioxidants (ethoxyquin, butylated hydroxytoluene and butylated hydroxyanisole) in fish feed and commercially farmed fish.  |  Lundebye, AK., et al. 2010. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 27: 1652-7. PMID: 20931417
  5. Investigations on the metabolism and potentially adverse effects of ethoxyquin dimer, a major metabolite of the synthetic antioxidant ethoxyquin in salmon muscle.  |  Ørnsrud, R., et al. 2011. J Food Prot. 74: 1574-80. PMID: 21902931
  6. Comprehensive characterization of ethoxyquin transformation products in fish feed by traveling-wave ion mobility spectrometry coupled to quadrupole time-of-flight mass spectrometry.  |  Negreira, N., et al. 2017. Anal Chim Acta. 965: 72-82. PMID: 28366214
  7. Comprehensive strategy for pesticide residue analysis through the production cycle of gilthead sea bream and Atlantic salmon.  |  Portolés, T., et al. 2017. Chemosphere. 179: 242-253. PMID: 28371708
  8. Liquid chromatography-electrochemical detection for the determination of ethoxyquin and its dimer in pear skin and salmon samples.  |  Rodríguez-Gómez, R., et al. 2018. Talanta. 177: 157-162. PMID: 29108570
  9. Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice.  |  Bernhard, A., et al. 2018. Food Chem Toxicol. 118: 608-625. PMID: 29883783
  10. Identification of ethoxyquin and its transformation products in salmon after controlled dietary exposure via fish feed.  |  Merel, S., et al. 2019. Food Chem. 289: 259-268. PMID: 30955610
  11. Modelling of the feed-to-fillet transfer of ethoxyquin and one of its main metabolites, ethoxyquin dimer, to the fillet of farmed Atlantic salmon (Salmon salar L.).  |  Berntssen, MHG., et al. 2019. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 36: 1042-1054. PMID: 31063084
  12. Analysis of ethoxyquin residues in animal feed using QuEChERS and gas chromatography tandem mass spectrometry and its results from Catalonian production 2018-2019.  |  Sanchez Costa, L., et al. 2020. Anal Methods. 12: 4080-4088. PMID: 32760978
  13. Analysis of ethoxyquin and its oxidation products in swine tissues by gas chromatography-tandem mass spectrometry for evaluating the feed-to-animal tissue transfer of ethoxyquin and its metabolites.  |  Zhang, C., et al. 2021. J Anim Sci Biotechnol. 12: 8. PMID: 33446269
  14. Safety and efficacy of a feed additive consisting of ethoxyquin (6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoline) for all animal species (FEFANA asbl).  |  , ., et al. 2022. EFSA J. 20: e07166. PMID: 35281649

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ethoxyquin Dimer, 1 mg

sc-214978A
1 mg
$270.00

Ethoxyquin Dimer, 2.5 mg

sc-214978
2.5 mg
$406.00