Ethoxyquin CAS: 91-53-2
MF: C14H19NO
MW: 217.31
A synthetic antioxidant which inhibits chemically induced carcinogenesis.

Ethoxyquin (CAS 91-53-2)

Ethoxyquin | CAS 91-53-2 is rated 5.0 out of 5 by 1.
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Alternate Names: EMQ; Santoflex; 1,2-Dihydro-6-ethoxy-2,2,4-trimethylquinoline
Application: Ethoxyquin is a synthetic antioxidant which inhibits chemically induced carcinogenesis
CAS Number: 91-53-2
Purity: ≥90%
Molecular Weight: 217.31
Molecular Formula: C14H19NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ethoxyquin acts as a synthetic antioxidant which inhibits chemically induced carcinogenesis, where it exerts its chemopreventive action by inducing glutathione synthetase and the phase II drug metabolizing enzyme, glutathione S-transferase (GST).


References

1. Hayes, J.D., et al. 1996. IARC Sci. Publ. 139: 175-187. PMID: 8923030
2. Shepherd, A.G., et al. 2000. Carcinogenesis. 21: 1827-1834. PMID: 11023540

Physical State :
Liquid
Solubility :
Soluble in acetone, methanol, ethanol, and chloroform. Insoluble in water.
Storage :
Store at room temperature
Melting Point :
<0° C
Boiling Point :
161° C (lit.) at 12 mmHg
Density :
1.03 g/mL at 20° C (lit.)
Refractive Index :
n20D 1.57
pK Values :
pKb: 5.02 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
RTECS :
VB8225000
PubChem CID :
Merck Index :
14: 3753
MDL Number :
MFCD00023883
EC Number :
202-075-7
Beilstein Registry :
158223
SMILES :
CCOC1=CC2=C(C=C1)NC(C=C2C)(C)C

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Zhu Zhu, J. et al. (PubMed 23955554) reported that Ethoxyquin prevents chemotherapy-induced neurotoxicity via Hsp90 modulation. -SCBT Publication Review
Date published: 2015-03-04
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